Sodium in PDB 7n27: Crystal Structure of Chromodomain of Cdyl in Complex with Inhibitor UNC6261

The structure of Crystal Structure of Chromodomain of Cdyl in Complex with Inhibitor UNC6261, PDB code: 7n27 was solved by S.Beldar, A.Dong, P.Loppnau, J.Min, C.H.Arrowsmith, A.M.Edwards, Structuralgenomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.64 / 1.85
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	62.971, 76.386, 80.628, 90, 90, 90
R / Rfree (%)	22.5 / 26.2

The structure of Crystal Structure of Chromodomain of Cdyl in Complex with Inhibitor UNC6261 also contains other interesting chemical elements:

Fluorine

(F)

30 atoms

The binding sites of Sodium atom in the Crystal Structure of Chromodomain of Cdyl in Complex with Inhibitor UNC6261 (pdb code 7n27). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of Chromodomain of Cdyl in Complex with Inhibitor UNC6261, PDB code: 7n27:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Crystal Structure of Chromodomain of Cdyl in Complex with Inhibitor UNC6261


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Chromodomain of Cdyl in Complex with Inhibitor UNC6261 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na201 b:40.2 occ:1.00 O A:GLU89 2.6 36.5 1.0 C A:GLU89 3.8 37.1 1.0 N A:ASP90 4.7 33.1 1.0 CA A:ASP90 4.7 31.8 1.0 CA A:GLU89 4.8 36.0 1.0 O A:ASP91 5.0 27.0 1.0 OD1 A:ASP90 5.0 39.6 1.0

Sodium binding site 2 out of 2 in the Crystal Structure of Chromodomain of Cdyl in Complex with Inhibitor UNC6261


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of Chromodomain of Cdyl in Complex with Inhibitor UNC6261 within 5.0Å range: probe atom residue distance (Å) B Occ D:Na201 b:22.8 occ:1.00 O D:HOH315 2.4 22.0 1.0 O D:VAL63 2.4 17.2 1.0 O D:HOH316 2.4 28.9 1.0 OH D:TYR105 2.5 18.0 1.0 CZ D:TYR105 3.6 17.6 1.0 C D:VAL63 3.6 18.9 1.0 CE2 D:TYR105 3.8 16.8 1.0 O J:HOH1101 3.9 28.4 1.0 CA D:GLU64 4.0 20.3 1.0 O D:GLU64 4.0 21.2 1.0 N D:GLU64 4.2 19.3 1.0 C D:GLU64 4.3 20.4 1.0 CG D:GLU62 4.7 26.2 1.0 CA D:VAL63 4.8 18.2 1.0 N D:VAL63 4.8 18.5 1.0 CE1 D:TYR105 4.8 18.5 1.0 O1 J:MN11000 4.9 18.4 1.0 C5 J:MN11000 4.9 17.8 1.0

S.Beldar, A.Dong, P.Loppnau, J.Min, C.H.Arrowsmith, A.M.Edwards, Structural Genomics Consortium (Sgc). Crystal Structure of Chromodomain of Cdyl in Complex with Inhibitor UNC6261 To Be Published.