Sodium in PDB 7mw7: Crystal Structure of P1G Mutant of D-Dopachrome Tautomerase

All present enzymatic activity of Crystal Structure of P1G Mutant of D-Dopachrome Tautomerase:
4.1.1.84;

The structure of Crystal Structure of P1G Mutant of D-Dopachrome Tautomerase, PDB code: 7mw7 was solved by R.Manjula, E.L.Murphy, J.W.Murphy, E.Lolis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.58 / 1.10
Space group	P 63
Cell size a, b, c (Å), α, β, γ (°)	73.993, 73.993, 41.067, 90, 90, 120
R / Rfree (%)	17.8 / 19

The binding sites of Sodium atom in the Crystal Structure of P1G Mutant of D-Dopachrome Tautomerase (pdb code 7mw7). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of P1G Mutant of D-Dopachrome Tautomerase, PDB code: 7mw7:

Sodium binding site 1 out of 1 in the Crystal Structure of P1G Mutant of D-Dopachrome Tautomerase


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of P1G Mutant of D-Dopachrome Tautomerase within 5.0Å range: probe atom residue distance (Å) B Occ A:Na202 b:28.4 occ:1.00 O A:HOH321 2.7 27.8 1.0 O4 A:SO4201 2.7 21.6 0.2 O A:HOH312 2.9 20.7 1.0 O1 A:SO4201 3.2 20.1 0.2 S A:SO4201 3.5 21.7 0.2 O3 A:SO4201 4.0 20.1 0.2 O A:HOH329 4.4 19.3 1.0 OE2 A:GLU4 4.6 29.3 1.0 OG A:SER62 4.7 14.7 0.7 OE1 A:GLU4 4.7 31.0 1.0 O2 A:SO4201 4.8 20.1 0.2 HG A:SER62 4.8 17.6 0.7 O A:HOH304 4.9 19.9 1.0 HB3 A:SER62 5.0 20.3 0.3

E.Chen, K.Reiss, D.Shah, R.Manjula, B.Allen, E.L.Murphy, J.W.Murphy, V.S.Batista, V.Bhandari, E.Lolis, G.P.Lisi. A Structurally Preserved Allosteric Site in the Mif Superfamily Affects Enzymatic Activity and CD74 Activation in D-Dopachrome Tautomerase J.Biol.Chem. 2021.
ISSN: ESSN 1083-351X
DOI: 10.1016/J.JBC.2021.101061