Sodium in PDB 7a2m: Crystal Structure of the Fyn SH3 Domain A95S-D99T Mutant in C21 Space Group

All present enzymatic activity of Crystal Structure of the Fyn SH3 Domain A95S-D99T Mutant in C21 Space Group:
2.7.10.2;

The structure of Crystal Structure of the Fyn SH3 Domain A95S-D99T Mutant in C21 Space Group, PDB code: 7a2m was solved by A.Camara-Artigas, M.Plaza-Garrido, M.C.Salinas-Garcia, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.70 / 1.50
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	72.694, 47.048, 42.712, 90, 97.42, 90
R / Rfree (%)	21.3 / 25.5

The binding sites of Sodium atom in the Crystal Structure of the Fyn SH3 Domain A95S-D99T Mutant in C21 Space Group (pdb code 7a2m). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Crystal Structure of the Fyn SH3 Domain A95S-D99T Mutant in C21 Space Group, PDB code: 7a2m:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in the Crystal Structure of the Fyn SH3 Domain A95S-D99T Mutant in C21 Space Group


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the Fyn SH3 Domain A95S-D99T Mutant in C21 Space Group within 5.0Å range: probe atom residue distance (Å) B Occ A:Na201 b:40.1 occ:1.00 O A:ASP100 2.3 33.4 1.0 O A:HOH325 2.3 42.8 1.0 O A:THR97 2.3 31.6 1.0 O A:HOH321 2.3 35.3 1.0 OG A:SER95 2.4 31.2 1.0 O A:HOH330 2.9 38.7 1.0 HA A:GLU98 3.0 46.7 1.0 HB2 A:SER95 3.1 33.3 1.0 CB A:SER95 3.3 27.7 1.0 C A:THR97 3.4 30.9 1.0 C A:ASP100 3.5 32.5 1.0 HB3 A:SER95 3.6 33.3 1.0 HA A:LEU101 3.6 38.3 1.0 H A:SER102 3.8 36.5 1.0 CA A:GLU98 3.8 38.9 1.0 HG A:SER102 3.8 35.4 1.0 C A:GLU98 4.0 37.4 1.0 N A:GLU98 4.1 44.4 1.0 O A:GLU98 4.2 42.1 1.0 H A:ASP100 4.2 40.6 1.0 H A:THR97 4.3 38.9 1.0 CA A:LEU101 4.3 32.1 1.0 N A:LEU101 4.3 34.8 1.0 N A:SER102 4.4 30.6 1.0 N A:ASP100 4.4 34.1 1.0 OD1 A:ASP100 4.4 32.1 1.0 CA A:ASP100 4.5 32.6 1.0 N A:THR97 4.6 32.4 1.0 CA A:SER95 4.6 29.4 1.0 CA A:THR97 4.6 31.6 1.0 OG A:SER102 4.7 29.7 1.0 C A:LEU101 4.7 30.5 1.0 N A:THR99 4.7 32.2 1.0 C A:SER95 4.8 31.2 1.0 CG A:ASP100 4.9 30.7 1.0 H A:GLU98 4.9 53.4 1.0 H A:SER95 5.0 32.1 1.0 HA A:THR97 5.0 37.7 1.0 H A:THR99 5.0 38.6 1.0

Sodium binding site 2 out of 3 in the Crystal Structure of the Fyn SH3 Domain A95S-D99T Mutant in C21 Space Group


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of the Fyn SH3 Domain A95S-D99T Mutant in C21 Space Group within 5.0Å range: probe atom residue distance (Å) B Occ A:Na202 b:40.2 occ:1.00 O A:VAL138 2.1 26.5 1.0 O A:SER135 2.6 29.9 1.0 HA A:ASN136 3.2 33.1 1.0 C A:VAL138 3.4 29.6 1.0 H A:VAL138 3.4 28.3 1.0 HA A:ALA139 3.6 30.2 1.0 C A:SER135 3.7 35.4 1.0 HG23 A:VAL138 3.8 29.6 1.0 CA A:ASN136 4.0 27.6 1.0 N A:VAL138 4.1 23.6 1.0 HD11 A:LEU90 4.3 37.3 1.0 N A:ALA139 4.3 23.9 1.0 CA A:VAL138 4.3 21.7 1.0 C A:ASN136 4.3 26.3 1.0 N A:ASN136 4.3 26.3 1.0 CA A:ALA139 4.4 25.1 1.0 HG22 A:VAL138 4.5 29.6 1.0 HB2 A:SER135 4.5 47.0 1.0 CG2 A:VAL138 4.5 24.6 1.0 HB2 A:ALA139 4.6 31.7 1.0 HE2 A:PHE87 4.7 42.9 1.0 O A:ASN136 4.7 29.4 1.0 N A:TYR137 4.8 24.2 1.0 HA A:SER135 4.8 37.2 1.0 CA A:SER135 4.8 30.9 1.0 HD12 A:LEU90 4.8 37.3 1.0 HD2 A:PHE87 4.8 39.8 1.0 HD3 A:PRO140 4.9 45.8 1.0 H A:TYR137 4.9 29.1 1.0

Sodium binding site 3 out of 3 in the Crystal Structure of the Fyn SH3 Domain A95S-D99T Mutant in C21 Space Group


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Crystal Structure of the Fyn SH3 Domain A95S-D99T Mutant in C21 Space Group within 5.0Å range: probe atom residue distance (Å) B Occ B:Na201 b:62.3 occ:1.00 O B:HOH338 2.4 45.3 1.0 O B:SER135 2.6 29.4 1.0 O B:HOH336 2.8 45.5 1.0 O B:VAL138 3.0 31.0 1.0 HH2 B:TRP120 3.3 37.7 1.0 HA B:ASN136 3.5 39.5 1.0 C B:SER135 3.5 31.4 1.0 HB2 B:SER135 3.7 42.6 1.0 CH2 B:TRP120 3.8 31.4 1.0 HG23 B:VAL138 4.1 38.3 1.0 HZ3 B:TRP120 4.1 36.4 1.0 H B:VAL138 4.1 33.0 1.0 HG22 B:VAL138 4.2 38.3 1.0 C B:VAL138 4.2 31.4 1.0 CZ3 B:TRP120 4.2 30.3 1.0 HA B:ALA139 4.2 36.2 1.0 CA B:ASN136 4.3 32.8 1.0 N B:ASN136 4.3 30.2 1.0 CB B:SER135 4.4 35.4 1.0 CA B:SER135 4.4 28.5 1.0 O B:HOH339 4.5 49.1 1.0 CZ2 B:TRP120 4.5 33.2 1.0 HA B:SER135 4.5 34.3 1.0 CG2 B:VAL138 4.6 31.9 1.0 HZ2 B:TRP120 4.6 39.9 1.0 OG B:SER135 4.6 35.4 1.0 C B:ASN136 4.8 26.0 1.0 N B:VAL138 4.9 27.5 1.0

A.Camara-Artigas, M.Plaza-Garrido, M.C.Salinas-Garcia. Crystal Structure of the Fyn SH3 Domain A95S-D99T Mutant in C21 Space Group To Be Published.