Sodium in PDB 6z50: Crystal Structure of CLK1 in Complex with Macrocycle ODS2003208

All present enzymatic activity of Crystal Structure of CLK1 in Complex with Macrocycle ODS2003208:
2.7.12.1;

The structure of Crystal Structure of CLK1 in Complex with Macrocycle ODS2003208, PDB code: 6z50 was solved by A.Chaikuad, P.Benderitter, J.Hoflack, A.Denis, S.Knapp, Structuralgenomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.65 / 1.60
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	69.173, 69.173, 330.581, 90.00, 90.00, 120.00
R / Rfree (%)	15.1 / 18

The binding sites of Sodium atom in the Crystal Structure of CLK1 in Complex with Macrocycle ODS2003208 (pdb code 6z50). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of CLK1 in Complex with Macrocycle ODS2003208, PDB code: 6z50:

Sodium binding site 1 out of 1 in the Crystal Structure of CLK1 in Complex with Macrocycle ODS2003208


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of CLK1 in Complex with Macrocycle ODS2003208 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na520 b:32.9 occ:1.00 O A:PRO475 2.8 17.2 1.0 O A:HOH822 2.8 39.4 1.0 OE1 A:GLU446 2.9 19.3 1.0 N A:LEU479 3.0 18.4 1.0 O A:PHE476 3.2 16.1 1.0 N A:ASP478 3.3 17.9 1.0 OE2 A:GLU446 3.4 21.4 1.0 CD A:GLU446 3.5 24.0 1.0 C A:PHE476 3.5 15.6 1.0 CG A:LEU479 3.6 22.2 1.0 CB A:ASP478 3.6 20.0 1.0 NH1 A:ARG449 3.6 17.3 0.5 CB A:LEU479 3.7 20.7 1.0 CA A:ASP478 3.7 19.4 1.0 C A:ASP478 3.8 18.9 1.0 CD1 A:LEU479 3.9 22.3 1.0 CA A:LEU479 3.9 19.8 1.0 C A:PRO475 3.9 18.1 1.0 CA A:PHE476 3.9 15.9 1.0 C A:PHE477 4.1 17.2 1.0 N A:PHE477 4.1 14.5 1.0 NE A:ARG266 4.2 15.4 1.0 N A:PHE476 4.4 17.3 1.0 CA A:PHE477 4.5 15.3 1.0 CD A:ARG449 4.5 22.6 0.5 CG A:ASP478 4.6 22.6 1.0 CD A:ARG449 4.6 15.2 0.5 O A:HOH1001 4.7 47.3 1.0 O A:HOH1000 4.7 49.7 1.0 CZ A:ARG449 4.7 17.8 0.5 NE A:ARG449 4.7 26.7 0.5 NH2 A:ARG266 4.8 16.0 1.0 CD A:ARG266 4.8 15.9 1.0 CZ A:ARG266 4.8 15.4 1.0 CG A:GLU446 4.8 23.6 1.0 O A:PHE477 4.9 18.8 1.0 O A:ASP478 4.9 20.1 1.0 CD2 A:LEU479 4.9 22.5 1.0

A.Chaikuad, P.Benderitter, J.Hoflack, A.Denis, S.Knapp, Structural Genomics Consortium (Sgc). Crystal Structure of CLK1 in Complex with Macrocycle ODS2003208 To Be Published.