Sodium in PDB 6yz2: Full Length Open-Form Sodium Channel Navms F208L

The structure of Full Length Open-Form Sodium Channel Navms F208L, PDB code: 6yz2 was solved by A.Sula, L.G.Sait, D.Hollingworth, B.A.Wallace, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	104.68 / 2.20
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	108.940, 108.940, 209.367, 90.00, 90.00, 90.00
R / Rfree (%)	24.3 / 26.5

The binding sites of Sodium atom in the Full Length Open-Form Sodium Channel Navms F208L (pdb code 6yz2). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Full Length Open-Form Sodium Channel Navms F208L, PDB code: 6yz2:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in the Full Length Open-Form Sodium Channel Navms F208L


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Full Length Open-Form Sodium Channel Navms F208L within 5.0Å range: probe atom residue distance (Å) B Occ A:Na301 b:81.1 occ:0.25 O A:THR176 4.9 37.7 1.0

Sodium binding site 2 out of 3 in the Full Length Open-Form Sodium Channel Navms F208L


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Full Length Open-Form Sodium Channel Navms F208L within 5.0Å range: probe atom residue distance (Å) B Occ A:Na302 b:97.0 occ:0.25 NA A:NA303 2.5 76.8 0.2 OE2 A:GLU178 4.3 44.6 1.0 N A:SER179 4.4 36.3 1.0 OG A:SER179 4.6 39.4 1.0

Sodium binding site 3 out of 3 in the Full Length Open-Form Sodium Channel Navms F208L


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Full Length Open-Form Sodium Channel Navms F208L within 5.0Å range: probe atom residue distance (Å) B Occ A:Na303 b:76.8 occ:0.25 NA A:NA302 2.5 97.0 0.2 O A:HOH420 3.7 60.6 1.0 OG A:SER179 3.8 39.4 1.0 OE2 A:GLU178 4.5 44.6 1.0 CB A:SER179 4.9 38.8 1.0

L.G.Sait, A.Sula, M.R.Ghovanloo, D.Hollingworth, P.C.Ruben, B.A.Wallace. Cannabidiol Interactions with Voltage-Gated Sodium Channels. Elife V. 9 2020.
ISSN: ESSN 2050-084X
PubMed: 33089780
DOI: 10.7554/ELIFE.58593