Sodium in PDB 6x2z: HEAAT3-Ofs-Asp

The binding sites of Sodium atom in the HEAAT3-Ofs-Asp (pdb code 6x2z). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the HEAAT3-Ofs-Asp, PDB code: 6x2z:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in the HEAAT3-Ofs-Asp


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of HEAAT3-Ofs-Asp within 5.0Å range: probe atom residue distance (Å) B Occ A:Na601 b:92.4 occ:1.00 O A:ASN366 2.1 93.8 1.0 OD2 A:ASP455 2.6 91.5 1.0 O A:GLY362 2.7 85.9 1.0 OD1 A:ASP455 3.1 91.5 1.0 CG A:ASP455 3.1 91.5 1.0 O A:ASN451 3.1 91.7 1.0 C A:ASN366 3.3 93.8 1.0 ND2 A:ASN366 3.5 93.8 1.0 C A:GLY362 3.6 85.9 1.0 CA A:ALA363 3.6 87.1 1.0 C A:ASN451 3.7 91.7 1.0 CB A:ASN451 3.8 91.7 1.0 O A:ALA363 4.0 87.1 1.0 N A:ALA363 4.1 87.1 1.0 C A:ALA363 4.1 87.1 1.0 CA A:ASN451 4.1 91.7 1.0 CA A:MET367 4.1 96.5 1.0 N A:MET367 4.1 96.5 1.0 CG A:MET367 4.2 96.5 1.0 CA A:ASN366 4.3 93.8 1.0 CG A:ASN366 4.3 93.8 1.0 OD1 A:ASN451 4.4 91.7 1.0 CG A:ASN451 4.4 91.7 1.0 CB A:ASN366 4.4 93.8 1.0 CB A:ASP455 4.4 91.5 1.0 N A:ASN366 4.6 93.8 1.0 N A:VAL452 4.6 87.7 1.0 CB A:MET367 4.7 96.5 1.0 OG A:SER333 4.7 83.1 1.0 CA A:GLY362 4.8 85.9 1.0 CB A:ALA363 4.8 87.1 1.0 CB A:SER333 4.9 83.1 1.0

Sodium binding site 2 out of 3 in the HEAAT3-Ofs-Asp


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of HEAAT3-Ofs-Asp within 5.0Å range: probe atom residue distance (Å) B Occ A:Na602 b:97.1 occ:1.00 O A:ALA408 2.5 101.9 1.0 O A:THR364 2.5 84.9 1.0 O A:SER405 2.5 104.2 1.0 O A:ILE406 2.6 99.5 1.0 SD A:MET367 2.6 96.5 1.0 C A:ILE406 3.1 99.5 1.0 C A:THR364 3.3 84.9 1.0 C A:ALA408 3.5 101.9 1.0 CA A:ILE406 3.6 99.5 1.0 N A:ALA408 3.6 101.9 1.0 C A:SER405 3.6 104.2 1.0 CG A:MET367 3.8 96.5 1.0 CA A:ALA408 4.0 101.9 1.0 N A:ILE365 4.0 87.0 1.0 N A:GLY407 4.0 102.2 1.0 N A:ILE406 4.1 99.5 1.0 CA A:ILE365 4.1 87.0 1.0 CA A:THR364 4.2 84.9 1.0 CE A:MET367 4.2 96.5 1.0 O A:ILE365 4.2 87.0 1.0 C A:GLY407 4.2 102.2 1.0 CB A:ALA408 4.3 101.9 1.0 C A:ILE365 4.4 87.0 1.0 CA A:GLY407 4.6 102.2 1.0 CB A:MET367 4.7 96.5 1.0 N A:ALA409 4.7 98.1 1.0 CA A:SER405 4.9 104.2 1.0 CB A:ILE406 5.0 99.5 1.0 CB A:THR364 5.0 84.9 1.0

Sodium binding site 3 out of 3 in the HEAAT3-Ofs-Asp


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of HEAAT3-Ofs-Asp within 5.0Å range: probe atom residue distance (Å) B Occ A:Na603 b:92.3 occ:1.00 OG1 A:THR102 2.2 94.6 1.0 OD1 A:ASN366 2.4 93.8 1.0 OD2 A:ASP368 2.4 98.4 1.0 OG1 A:THR101 2.6 92.0 1.0 O A:TYR98 2.6 88.2 1.0 N A:THR102 3.1 94.6 1.0 CG A:ASN366 3.4 93.8 1.0 CG A:ASP368 3.4 98.4 1.0 CB A:THR102 3.4 94.6 1.0 C A:TYR98 3.5 88.2 1.0 CA A:THR102 3.6 94.6 1.0 OD1 A:ASP368 3.6 98.4 1.0 CA A:TYR98 3.7 88.2 1.0 CB A:ASN366 3.7 93.8 1.0 CB A:THR101 3.8 92.0 1.0 C A:THR101 3.9 92.0 1.0 CA A:ASN366 3.9 93.8 1.0 CB A:TYR98 4.2 88.2 1.0 CA A:THR101 4.3 92.0 1.0 C A:ASN366 4.5 93.8 1.0 N A:THR101 4.5 92.0 1.0 CG2 A:THR102 4.6 94.6 1.0 ND2 A:ASN366 4.6 93.8 1.0 N A:MET367 4.6 96.5 1.0 O A:THR101 4.7 92.0 1.0 O A:TYR97 4.7 89.4 1.0 N A:PHE99 4.7 92.5 1.0 CD1 A:TYR98 4.8 88.2 1.0 CB A:ASP368 4.8 98.4 1.0 CG A:TYR98 4.8 88.2 1.0 N A:ASP368 4.8 98.4 1.0 N A:TYR98 5.0 88.2 1.0 CG2 A:THR101 5.0 92.0 1.0

B.Qiu, D.Matthies, E.Fortea, Z.Yu, O.Boudker. Cryo-Em Structures of Excitatory Amino Acid Transporter 3 Visualize Coupled Substrate, Sodium, and Proton Binding and Transport. Sci Adv V. 7 2021.
ISSN: ESSN 2375-2548
PubMed: 33658209
DOI: 10.1126/SCIADV.ABF5814