Sodium in PDB 6t5i: The Transcriptional Regulator Prfa From Listeria Monocytogenes in Complex with Inhibitor of Wnt Production (Iwp)-2

The structure of The Transcriptional Regulator Prfa From Listeria Monocytogenes in Complex with Inhibitor of Wnt Production (Iwp)-2, PDB code: 6t5i was solved by M.Oelker, C.Grundstrom, A.Blumenthal, A.E.Sauer-Eriksson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.33 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	47.951, 92.667, 101.447, 90, 90, 90
R / Rfree (%)	19.9 / 25.2

The binding sites of Sodium atom in the The Transcriptional Regulator Prfa From Listeria Monocytogenes in Complex with Inhibitor of Wnt Production (Iwp)-2 (pdb code 6t5i). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the The Transcriptional Regulator Prfa From Listeria Monocytogenes in Complex with Inhibitor of Wnt Production (Iwp)-2, PDB code: 6t5i:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the The Transcriptional Regulator Prfa From Listeria Monocytogenes in Complex with Inhibitor of Wnt Production (Iwp)-2


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of The Transcriptional Regulator Prfa From Listeria Monocytogenes in Complex with Inhibitor of Wnt Production (Iwp)-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na308 b:42.2 occ:1.00 O A:HOH440 2.3 45.5 1.0 O A:ASN30 2.4 29.9 1.0 O A:HOH414 2.6 34.8 1.0 OE1 A:GLU36 3.4 39.4 1.0 O A:ASP33 3.4 39.9 1.0 C A:ASN30 3.5 31.2 1.0 O A:HOH412 3.7 42.2 1.0 CD1 A:PHE29 3.9 26.4 1.0 CB A:ASP33 4.0 44.1 1.0 O A:GLN35 4.0 33.6 1.0 N A:ASN30 4.1 27.8 1.0 O A:TYR83 4.2 28.3 1.0 OE2 A:GLU36 4.2 41.7 1.0 CD A:GLU36 4.2 38.8 1.0 C A:ASP33 4.3 44.1 1.0 N A:ASP33 4.4 41.5 1.0 CA A:GLN31 4.4 35.1 1.0 N A:GLN31 4.4 28.6 1.0 O A:HOH426 4.4 42.1 1.0 OG A:SER71 4.4 28.2 1.0 CB A:PHE29 4.4 29.8 1.0 CA A:ASN30 4.4 29.9 1.0 CA A:ASP33 4.5 37.7 1.0 CG A:PHE29 4.5 32.7 1.0 CB A:SER71 4.6 33.5 1.0 C A:GLN31 4.7 40.4 1.0 CE1 A:PHE29 4.7 39.3 1.0 C A:PHE29 4.8 28.4 1.0 C2 A:DMS302 4.9 48.3 1.0 CG A:ASP33 4.9 46.8 1.0

Sodium binding site 2 out of 2 in the The Transcriptional Regulator Prfa From Listeria Monocytogenes in Complex with Inhibitor of Wnt Production (Iwp)-2


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of The Transcriptional Regulator Prfa From Listeria Monocytogenes in Complex with Inhibitor of Wnt Production (Iwp)-2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Na406 b:52.1 occ:1.00 O B:HOH505 2.3 43.3 1.0 O B:ASN30 2.5 30.6 1.0 O B:HOH522 2.6 27.6 1.0 OE1 B:GLU36 3.0 40.1 1.0 O B:HOH519 3.2 53.2 1.0 C B:ASN30 3.6 32.5 1.0 O B:ASP33 3.7 48.0 1.0 CD B:GLU36 3.8 43.2 1.0 OE2 B:GLU36 3.9 42.0 1.0 CB B:ASP33 4.0 40.8 1.0 O B:GLN35 4.1 34.1 1.0 N B:ASN30 4.1 33.6 1.0 CD1 B:PHE29 4.2 25.5 1.0 OG B:SER71 4.3 25.6 1.0 O B:TYR83 4.4 28.6 1.0 CB B:SER71 4.4 28.6 1.0 N B:GLN31 4.4 36.2 1.0 CA B:GLN31 4.4 35.7 1.0 N B:ASP33 4.5 38.8 1.0 O B:HOH508 4.5 32.1 1.0 CA B:ASN30 4.5 33.8 1.0 CB B:PHE29 4.5 30.7 1.0 C B:ASP33 4.6 40.1 1.0 CA B:ASP33 4.6 35.7 1.0 CG B:PHE29 4.7 28.1 1.0 C B:GLN31 4.7 44.7 1.0 C B:PHE29 5.0 31.6 1.0 CE1 B:PHE29 5.0 33.1 1.0

T.T.Tran, M.G.Andrades, C.Mathmann, R.F.Rollo, M.Oelker, T.T.K.Nguyen, A.Zamoshnikova, L.K.Kummari, O.J.K.Wyer, K.M.Irvine, J.N.Melo-Bolivar, A.Gross, D.Brown, J.Y.W.Mak, K.Hansford, D.P.Fairlie, R.Giri, V.Schreiber, S.Joseph, F.Simpson, T.Barnett, T.Wells, R.Kapetanovic, M.J.Sweet, E.Latomanski, H.Newton, R.J.R.Guerillot, A.Hachani, T.P.Stinear, S.Y.Ong, Y.Chandran, E.Hartland, B.Kobe, J.L.Stow, A.E.Sauer-Eriksson, J.Begun, J.C.Kling, A.Blumenthal. Rapid Replication of Listeria Monocytogenes in Spacious Intracellular Vacuoles and Progressive Bacterial Elimination From Infected Macrophages Upon Inhibition of Prfa-Controlled Virulence Factor Expression To Be Published.