Sodium in PDB 6sx7: Crystal Structure of the Voltage-Gated Sodium Channel Navms (F208L) (2.2 Angstrom Resolution)

The structure of Crystal Structure of the Voltage-Gated Sodium Channel Navms (F208L) (2.2 Angstrom Resolution), PDB code: 6sx7 was solved by A.Sula, D.Hollingworth, B.A.Wallace, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.25 / 2.50
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	109.004, 109.004, 208.827, 90, 90, 90
R / Rfree (%)	23.2 / 24.7

The binding sites of Sodium atom in the Crystal Structure of the Voltage-Gated Sodium Channel Navms (F208L) (2.2 Angstrom Resolution) (pdb code 6sx7). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Crystal Structure of the Voltage-Gated Sodium Channel Navms (F208L) (2.2 Angstrom Resolution), PDB code: 6sx7:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in the Crystal Structure of the Voltage-Gated Sodium Channel Navms (F208L) (2.2 Angstrom Resolution)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the Voltage-Gated Sodium Channel Navms (F208L) (2.2 Angstrom Resolution) within 5.0Å range: probe atom residue distance (Å) B Occ A:Na301 b:84.5 occ:0.25 O A:THR176 4.8 45.1 1.0

Sodium binding site 2 out of 3 in the Crystal Structure of the Voltage-Gated Sodium Channel Navms (F208L) (2.2 Angstrom Resolution)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of the Voltage-Gated Sodium Channel Navms (F208L) (2.2 Angstrom Resolution) within 5.0Å range: probe atom residue distance (Å) B Occ A:Na302 b:71.2 occ:0.25 NA A:NA303 3.0 81.9 0.2 N A:SER179 4.5 40.7 1.0 OE2 A:GLU178 4.5 51.4 1.0 OG A:SER179 4.8 47.1 1.0

Sodium binding site 3 out of 3 in the Crystal Structure of the Voltage-Gated Sodium Channel Navms (F208L) (2.2 Angstrom Resolution)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Crystal Structure of the Voltage-Gated Sodium Channel Navms (F208L) (2.2 Angstrom Resolution) within 5.0Å range: probe atom residue distance (Å) B Occ A:Na303 b:81.9 occ:0.25 NA A:NA302 3.0 71.2 0.2 OG A:SER179 3.7 47.1 1.0 O A:HOH422 3.8 60.3 1.0 OE2 A:GLU178 4.5 51.4 1.0 CB A:SER179 4.8 40.3 1.0

A.Sula, D.Hollingworth, L.C.Ng, M.Larmore, P.G.Decaen, B.A.Wallace. A Tamoxifen Receptor Within A Voltage-Gated Sodium Channel Mol.Cell 2021.
ISSN: ISSN 1097-2765
DOI: 10.1016/J.MOLCEL.2020.12.048