Sodium in PDB 6sx5: Full Length Mutant Open-Form Sodium Channel Navms

The structure of Full Length Mutant Open-Form Sodium Channel Navms, PDB code: 6sx5 was solved by A.Sula, D.Hollingworth, B.A.Wallace, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.80 / 2.20
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	109.133, 109.133, 209.031, 90, 90, 90
R / Rfree (%)	22 / 24.8

The binding sites of Sodium atom in the Full Length Mutant Open-Form Sodium Channel Navms (pdb code 6sx5). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Full Length Mutant Open-Form Sodium Channel Navms, PDB code: 6sx5:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in the Full Length Mutant Open-Form Sodium Channel Navms


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Full Length Mutant Open-Form Sodium Channel Navms within 5.0Å range: probe atom residue distance (Å) B Occ A:Na301 b:75.3 occ:0.25 O A:THR176 4.8 27.4 1.0

Sodium binding site 2 out of 3 in the Full Length Mutant Open-Form Sodium Channel Navms


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Full Length Mutant Open-Form Sodium Channel Navms within 5.0Å range: probe atom residue distance (Å) B Occ A:Na302 b:74.4 occ:0.25 NA A:NA303 2.4 72.8 0.2 OE2 A:GLU178 4.3 37.8 1.0 N A:SER179 4.4 26.5 1.0 OG A:SER179 4.4 31.4 1.0 CA A:SER179 4.9 27.4 1.0

Sodium binding site 3 out of 3 in the Full Length Mutant Open-Form Sodium Channel Navms


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Full Length Mutant Open-Form Sodium Channel Navms within 5.0Å range: probe atom residue distance (Å) B Occ A:Na303 b:72.8 occ:0.25 NA A:NA302 2.4 74.4 0.2 O A:HOH410 3.7 57.8 1.0 OG A:SER179 3.8 31.4 1.0 OE2 A:GLU178 4.5 37.8 1.0 CB A:SER179 4.9 30.4 1.0

A.Sula, D.Hollingworth, L.C.Ng, M.Larmore, P.G.Decaen, B.A.Wallace. A Tamoxifen Receptor Within A Voltage-Gated Sodium Channel Mol.Cell 2021.
ISSN: ISSN 1097-2765
DOI: 10.1016/J.MOLCEL.2020.12.048