Sodium in PDB 6qlm: Cathepsin-K in Complex with Miv-701

All present enzymatic activity of Cathepsin-K in Complex with Miv-701:
3.4.22.38;

The structure of Cathepsin-K in Complex with Miv-701, PDB code: 6qlm was solved by D.J.Derbyshire, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	53.79 / 1.50
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	34.537, 51.855, 57.260, 74.34, 76.39, 84.70
R / Rfree (%)	10.1 / 14.2

The structure of Cathepsin-K in Complex with Miv-701 also contains other interesting chemical elements:

Fluorine

(F)

2 atoms

The binding sites of Sodium atom in the Cathepsin-K in Complex with Miv-701 (pdb code 6qlm). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Cathepsin-K in Complex with Miv-701, PDB code: 6qlm:

Sodium binding site 1 out of 1 in the Cathepsin-K in Complex with Miv-701


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Cathepsin-K in Complex with Miv-701 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na303 b:7.3 occ:1.00 OD1 B:ASN70 2.3 6.3 1.0 OD1 A:ASN70 2.4 6.1 1.0 OE1 B:GLU59 2.4 7.4 1.0 OE2 A:GLU59 2.5 7.8 1.0 O B:HOH498 2.5 10.4 1.0 O A:HOH534 2.6 16.3 1.0 CD B:GLU59 3.2 7.7 1.0 CD A:GLU59 3.3 7.2 1.0 CG B:ASN70 3.5 6.0 1.0 CG A:ASN70 3.5 5.4 1.0 OE2 B:GLU59 3.6 7.7 1.0 OE1 A:GLU59 3.7 8.1 1.0 CA B:ASN70 4.3 5.8 1.0 CB B:ASN70 4.3 6.0 1.0 CG B:GLU59 4.3 7.7 1.0 CA A:ASN70 4.3 5.0 1.0 CB A:ASN70 4.3 4.9 1.0 ND2 B:ASN70 4.4 6.0 1.0 CG A:GLU59 4.4 6.6 1.0 ND2 A:ASN70 4.4 5.7 1.0 O B:HOH464 4.5 8.4 1.0 O A:HOH446 4.6 7.8 1.0 CB B:GLU59 4.6 7.1 1.0 CB A:GLU59 4.6 6.2 1.0 CG B:GLN73 4.7 10.3 1.0 CG A:GLN73 4.7 8.3 1.0 CB B:GLN73 4.8 8.5 1.0 CB A:GLN73 4.9 7.2 1.0 N B:ASN70 4.9 5.7 1.0 N A:ASN70 4.9 5.1 1.0

D.J.Derbyshire, D.J.Derbyshire. N/A N/A.