Sodium in PDB 6qav: Crystal Structure of ULK2 in Complexed with MRT68921

All present enzymatic activity of Crystal Structure of ULK2 in Complexed with MRT68921:
2.7.11.1;

The structure of Crystal Structure of ULK2 in Complexed with MRT68921, PDB code: 6qav was solved by A.Chaikuad, C.H.Arrowsmith, A.M.Edwards, C.Bountra, S.Knapp, Structuralgenomics Consortium, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	57.97 / 2.05
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	74.648, 69.050, 107.710, 90.00, 97.93, 90.00
R / Rfree (%)	19.5 / 23.1

The binding sites of Sodium atom in the Crystal Structure of ULK2 in Complexed with MRT68921 (pdb code 6qav). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of ULK2 in Complexed with MRT68921, PDB code: 6qav:

Sodium binding site 1 out of 1 in the Crystal Structure of ULK2 in Complexed with MRT68921


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of ULK2 in Complexed with MRT68921 within 5.0Å range: probe atom residue distance (Å) B Occ B:Na302 b:41.9 occ:1.00 O B:HOH466 2.3 30.1 1.0 O B:HOH483 2.3 52.3 1.0 O B:HOH444 2.5 36.4 1.0 O B:LEU63 2.5 33.9 1.0 O B:LYS61 2.5 31.2 1.0 O B:LEU60 2.6 29.4 1.0 C B:LYS61 3.1 32.5 1.0 CA B:LYS61 3.5 32.8 1.0 C B:LEU60 3.6 28.6 1.0 C B:LEU63 3.6 34.1 1.0 O B:HOH448 3.8 26.0 1.0 N B:LEU63 4.0 33.5 1.0 N B:LYS61 4.0 29.5 1.0 N B:GLU62 4.1 32.7 1.0 C B:GLU62 4.4 33.8 1.0 CA B:LEU63 4.4 34.0 1.0 N B:GLN64 4.6 35.1 1.0 O B:LEU71 4.6 26.4 1.0 NE2 B:GLN64 4.7 60.0 1.0 N B:LEU71 4.7 25.9 1.0 CA B:GLU62 4.7 33.7 1.0 CA B:GLN64 4.8 38.0 1.0 CB B:LEU71 4.8 25.8 1.0 CB B:GLN64 4.9 42.3 1.0 CB B:LYS61 4.9 34.6 1.0 CA B:LEU60 4.9 26.9 1.0 CD B:GLN64 5.0 54.5 1.0

A.Chaikuad, S.E.Koschade, A.Stolz, K.Zivkovic, C.Pohl, S.Shaid, H.Ren, L.J.Lambert, N.D.P.Cosford, C.H.Brandts, S.Knapp. Conservation of Structure, Function and Inhibitor Binding in Unc-51-Like Kinase 1 and 2 (ULK1/2). Biochem.J. V. 476 875 2019.
ISSN: ESSN 1470-8728
PubMed: 30782972
DOI: 10.1042/BCJ20190038