Sodium in PDB 6i3z: Fab Fragment of An Antibody Selective For Wild-Type Alpha-1- Antitrypsin in Complex with Its Antigen

The structure of Fab Fragment of An Antibody Selective For Wild-Type Alpha-1- Antitrypsin in Complex with Its Antigen, PDB code: 6i3z was solved by M.Laffranchi, E.L.K.Elliston, E.Miranda, J.Perez, A.M.Jagger, A.Fra, D.A.Lomas, J.A.Irving, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.82 / 3.10
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	37.538, 51.930, 105.869, 84.31, 81.47, 78.95
R / Rfree (%)	26.1 / 30.7

The binding sites of Sodium atom in the Fab Fragment of An Antibody Selective For Wild-Type Alpha-1- Antitrypsin in Complex with Its Antigen (pdb code 6i3z). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Fab Fragment of An Antibody Selective For Wild-Type Alpha-1- Antitrypsin in Complex with Its Antigen, PDB code: 6i3z:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Fab Fragment of An Antibody Selective For Wild-Type Alpha-1- Antitrypsin in Complex with Its Antigen


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Fab Fragment of An Antibody Selective For Wild-Type Alpha-1- Antitrypsin in Complex with Its Antigen within 5.0Å range: probe atom residue distance (Å) B Occ A:Na401 b:27.7 occ:1.00 CB A:VAL216 3.8 22.7 1.0 CG1 A:VAL216 3.9 31.7 1.0 CA A:VAL216 4.0 35.4 1.0 N A:LYS217 4.0 25.6 1.0 C A:VAL216 4.6 35.0 1.0 O A:LYS217 4.8 23.2 1.0

Sodium binding site 2 out of 2 in the Fab Fragment of An Antibody Selective For Wild-Type Alpha-1- Antitrypsin in Complex with Its Antigen


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Fab Fragment of An Antibody Selective For Wild-Type Alpha-1- Antitrypsin in Complex with Its Antigen within 5.0Å range: probe atom residue distance (Å) B Occ L:Na301 b:27.7 occ:1.00 O L:HOH409 3.1 18.3 1.0 O L:ASP56 3.3 36.1 1.0 CA L:GLY57 4.0 19.0 1.0 C L:GLY57 4.1 25.8 1.0 C L:ASP56 4.3 30.9 1.0 O L:GLY57 4.3 26.5 1.0 CG1 L:VAL55 4.6 30.0 1.0 CG2 L:VAL58 4.6 17.7 1.0 N L:GLY57 4.6 30.6 1.0 N L:VAL58 4.6 26.8 1.0

M.Laffranchi, E.L.K.Elliston, E.Miranda, J.Perez, N.Heyer-Chauhan, F.Gangemi, A.M.Jagger, A.Fra, J.A.Irving, D.A.Lomas. Characterisation of Polymers Extracted From the Liver Tissue of Individuals with the Mz Alpha-1-Antitrypsin Deficiency Genotype To Be Published.