Sodium in PDB 6erc: Peroxidase A From Dictyostelium Discoideum (Ddpoxa)
Enzymatic activity of Peroxidase A From Dictyostelium Discoideum (Ddpoxa)
All present enzymatic activity of Peroxidase A From Dictyostelium Discoideum (Ddpoxa):
1.11.1.7;
Protein crystallography data
The structure of Peroxidase A From Dictyostelium Discoideum (Ddpoxa), PDB code: 6erc
was solved by
A.Nicolussi,
G.Mlynek,
P.G.Furtmueller,
K.Djinovic-Carugo,
C.Obinger,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
48.67 /
2.50
|
Space group
|
P 31 2 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
128.253,
128.253,
146.015,
90.00,
90.00,
120.00
|
R / Rfree (%)
|
22.8 /
25.7
|
Other elements in 6erc:
The structure of Peroxidase A From Dictyostelium Discoideum (Ddpoxa) also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Peroxidase A From Dictyostelium Discoideum (Ddpoxa)
(pdb code 6erc). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the
Peroxidase A From Dictyostelium Discoideum (Ddpoxa), PDB code: 6erc:
Jump to Sodium binding site number:
1;
2;
Sodium binding site 1 out
of 2 in 6erc
Go back to
Sodium Binding Sites List in 6erc
Sodium binding site 1 out
of 2 in the Peroxidase A From Dictyostelium Discoideum (Ddpoxa)
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 1 of Peroxidase A From Dictyostelium Discoideum (Ddpoxa) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na609
b:57.0
occ:1.00
|
O
|
A:TYR169
|
2.3
|
54.0
|
1.0
|
OD1
|
A:ASN173
|
2.4
|
58.1
|
1.0
|
O
|
A:ASN102
|
2.4
|
56.1
|
1.0
|
OD1
|
A:ASP171
|
2.5
|
59.2
|
1.0
|
O
|
A:GLY167
|
2.6
|
55.9
|
1.0
|
CG
|
A:ASP171
|
3.3
|
59.0
|
1.0
|
CG
|
A:ASN173
|
3.4
|
59.2
|
1.0
|
C
|
A:GLY167
|
3.4
|
56.1
|
1.0
|
C
|
A:ASN102
|
3.4
|
55.9
|
1.0
|
H
|
A:ASP171
|
3.4
|
69.0
|
1.0
|
HA3
|
A:GLY167
|
3.5
|
68.8
|
1.0
|
O
|
A:HOH706
|
3.5
|
58.4
|
1.0
|
C
|
A:TYR169
|
3.5
|
53.0
|
1.0
|
OD2
|
A:ASP171
|
3.5
|
60.3
|
1.0
|
O
|
A:HOH781
|
3.6
|
46.1
|
1.0
|
HB3
|
A:ASN173
|
3.6
|
72.3
|
1.0
|
HA
|
A:ASN102
|
3.9
|
67.3
|
1.0
|
HA
|
A:MET103
|
3.9
|
66.5
|
1.0
|
CA
|
A:GLY167
|
3.9
|
57.4
|
1.0
|
H
|
A:TYR169
|
3.9
|
68.0
|
1.0
|
HA
|
A:ILE170
|
4.0
|
66.2
|
1.0
|
N
|
A:TYR169
|
4.1
|
56.7
|
1.0
|
CB
|
A:ASN173
|
4.1
|
60.2
|
1.0
|
H
|
A:GLY167
|
4.1
|
71.6
|
1.0
|
H
|
A:ASN173
|
4.1
|
69.9
|
1.0
|
N
|
A:ASP171
|
4.1
|
57.5
|
1.0
|
CA
|
A:ASN102
|
4.2
|
56.1
|
1.0
|
HB3
|
A:ASN102
|
4.2
|
68.0
|
1.0
|
N
|
A:GLY167
|
4.2
|
59.7
|
1.0
|
HG
|
A:LEU166
|
4.3
|
69.3
|
1.0
|
N
|
A:MET103
|
4.3
|
57.5
|
1.0
|
ND2
|
A:ASN173
|
4.3
|
59.3
|
1.0
|
CA
|
A:TYR169
|
4.4
|
54.9
|
1.0
|
HD21
|
A:ASN173
|
4.4
|
71.2
|
1.0
|
N
|
A:SER168
|
4.4
|
55.9
|
1.0
|
C
|
A:SER168
|
4.5
|
54.3
|
1.0
|
CB
|
A:ASP171
|
4.5
|
59.2
|
1.0
|
N
|
A:ILE170
|
4.5
|
52.1
|
1.0
|
HD23
|
A:LEU166
|
4.5
|
70.4
|
1.0
|
CA
|
A:MET103
|
4.5
|
55.4
|
1.0
|
HB2
|
A:TYR169
|
4.6
|
65.8
|
1.0
|
CA
|
A:ILE170
|
4.7
|
55.2
|
1.0
|
HB2
|
A:ASN173
|
4.7
|
72.3
|
1.0
|
HB3
|
A:ASP171
|
4.7
|
71.0
|
1.0
|
CB
|
A:ASN102
|
4.7
|
56.6
|
1.0
|
HA2
|
A:GLY167
|
4.8
|
68.8
|
1.0
|
CA
|
A:ASP171
|
4.8
|
57.8
|
1.0
|
N
|
A:ASN173
|
4.9
|
58.3
|
1.0
|
CA
|
A:SER168
|
4.9
|
54.9
|
1.0
|
HA
|
A:SER168
|
4.9
|
65.8
|
1.0
|
C
|
A:ILE170
|
4.9
|
56.5
|
1.0
|
|
Sodium binding site 2 out
of 2 in 6erc
Go back to
Sodium Binding Sites List in 6erc
Sodium binding site 2 out
of 2 in the Peroxidase A From Dictyostelium Discoideum (Ddpoxa)
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 2 of Peroxidase A From Dictyostelium Discoideum (Ddpoxa) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Na606
b:68.7
occ:1.00
|
O
|
B:TYR169
|
2.4
|
79.2
|
1.0
|
O
|
B:ASN102
|
2.4
|
76.8
|
1.0
|
OD1
|
B:ASP171
|
2.4
|
81.3
|
1.0
|
OD1
|
B:ASN173
|
2.5
|
77.4
|
1.0
|
O
|
B:GLY167
|
2.7
|
80.4
|
1.0
|
H
|
B:ASP171
|
3.1
|
96.2
|
1.0
|
CG
|
B:ASP171
|
3.1
|
82.5
|
1.0
|
OD2
|
B:ASP171
|
3.4
|
83.9
|
1.0
|
C
|
B:ASN102
|
3.4
|
76.0
|
1.0
|
C
|
B:GLY167
|
3.4
|
80.7
|
1.0
|
HA3
|
B:GLY167
|
3.5
|
98.2
|
1.0
|
CG
|
B:ASN173
|
3.5
|
77.3
|
1.0
|
C
|
B:TYR169
|
3.6
|
79.0
|
1.0
|
HB3
|
B:ASN173
|
3.7
|
94.1
|
1.0
|
HA
|
B:MET103
|
3.8
|
92.0
|
1.0
|
CA
|
B:GLY167
|
3.8
|
81.8
|
1.0
|
H
|
B:GLY167
|
3.9
|
97.0
|
1.0
|
H
|
B:ASN173
|
3.9
|
93.8
|
1.0
|
N
|
B:ASP171
|
3.9
|
80.1
|
1.0
|
HA
|
B:ASN102
|
3.9
|
89.9
|
1.0
|
HA
|
B:ILE170
|
4.0
|
91.6
|
1.0
|
H
|
B:TYR169
|
4.1
|
95.6
|
1.0
|
HB3
|
B:ASN102
|
4.1
|
90.6
|
1.0
|
N
|
B:GLY167
|
4.2
|
80.8
|
1.0
|
N
|
B:TYR169
|
4.2
|
79.7
|
1.0
|
CB
|
B:ASN173
|
4.2
|
78.5
|
1.0
|
CA
|
B:ASN102
|
4.2
|
74.9
|
1.0
|
N
|
B:MET103
|
4.3
|
75.7
|
1.0
|
CB
|
B:ASP171
|
4.4
|
81.8
|
1.0
|
HB3
|
B:LEU166
|
4.4
|
90.5
|
1.0
|
CA
|
B:TYR169
|
4.5
|
79.8
|
1.0
|
N
|
B:SER168
|
4.5
|
79.7
|
1.0
|
N
|
B:ILE170
|
4.5
|
77.1
|
1.0
|
CA
|
B:MET103
|
4.5
|
76.7
|
1.0
|
ND2
|
B:ASN173
|
4.6
|
76.2
|
1.0
|
C
|
B:SER168
|
4.6
|
78.4
|
1.0
|
HB2
|
B:TYR169
|
4.6
|
95.5
|
1.0
|
CA
|
B:ILE170
|
4.6
|
76.3
|
1.0
|
HB3
|
B:ASP171
|
4.6
|
98.2
|
1.0
|
HD21
|
B:ASN173
|
4.7
|
91.4
|
1.0
|
CA
|
B:ASP171
|
4.7
|
80.9
|
1.0
|
HD22
|
B:LEU166
|
4.7
|
90.7
|
1.0
|
CB
|
B:ASN102
|
4.7
|
75.5
|
1.0
|
N
|
B:ASN173
|
4.7
|
78.2
|
1.0
|
H
|
B:GLY172
|
4.7
|
92.4
|
1.0
|
HA2
|
B:GLY167
|
4.8
|
98.2
|
1.0
|
C
|
B:ILE170
|
4.8
|
77.6
|
1.0
|
HB2
|
B:ASN173
|
4.8
|
94.1
|
1.0
|
HA
|
B:SER168
|
4.9
|
94.9
|
1.0
|
CA
|
B:SER168
|
4.9
|
79.1
|
1.0
|
|
Reference:
A.Nicolussi,
J.D.Dunn,
G.Mlynek,
M.Bellei,
M.Zamocky,
G.Battistuzzi,
K.Djinovic-Carugo,
P.G.Furtmuller,
T.Soldati,
C.Obinger.
Secreted Heme Peroxidase From Dictyostelium Discoideum: Insights Into Catalysis, Structure, and Biological Role. J. Biol. Chem. V. 293 1330 2018.
ISSN: ESSN 1083-351X
PubMed: 29242189
DOI: 10.1074/JBC.RA117.000463
Page generated: Tue Oct 8 08:31:43 2024
|