Sodium in PDB 6emj: Fab Fragment. Abvance: Increasing Our Knowledge of Antibody Structural Space to Enable Faster and Better Decision Making in Antibody Drug Discovery

The structure of Fab Fragment. Abvance: Increasing Our Knowledge of Antibody Structural Space to Enable Faster and Better Decision Making in Antibody Drug Discovery, PDB code: 6emj was solved by J.Benz, S.Weigand, S.Dengl, T.Schlothauer, J.Auer, A.Ehler, H.Kettenberger, S.Lorenz, T.Hirschheydt, G.Georges, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.79 / 2.30
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	51.480, 73.869, 76.920, 69.34, 78.05, 70.20
R / Rfree (%)	16.5 / 21.1

The binding sites of Sodium atom in the Fab Fragment. Abvance: Increasing Our Knowledge of Antibody Structural Space to Enable Faster and Better Decision Making in Antibody Drug Discovery (pdb code 6emj). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Fab Fragment. Abvance: Increasing Our Knowledge of Antibody Structural Space to Enable Faster and Better Decision Making in Antibody Drug Discovery, PDB code: 6emj:

Sodium binding site 1 out of 1 in the Fab Fragment. Abvance: Increasing Our Knowledge of Antibody Structural Space to Enable Faster and Better Decision Making in Antibody Drug Discovery


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Fab Fragment. Abvance: Increasing Our Knowledge of Antibody Structural Space to Enable Faster and Better Decision Making in Antibody Drug Discovery within 5.0Å range: probe atom residue distance (Å) B Occ A:Na301 b:65.6 occ:1.00 O A:SER63 2.5 44.6 1.0 NH1 A:ARG87 3.1 34.7 1.0 C A:SER63 3.5 44.4 1.0 NH2 A:ARG87 3.6 40.3 1.0 CZ A:ARG87 3.8 55.6 1.0 CB A:SER63 3.9 37.9 1.0 CD2 A:LEU64 4.0 43.4 1.0 OE1 A:GLN67 4.1 40.4 1.0 CA A:SER63 4.2 37.7 1.0 OG A:SER63 4.2 38.7 1.0 OE1 A:GLU89 4.5 76.9 1.0 O A:HOH422 4.5 36.1 1.0 N A:LEU64 4.5 41.3 1.0 CA A:LEU64 4.7 40.2 1.0 CG A:LEU64 4.8 42.8 1.0 CD A:GLN67 4.9 55.0 1.0

J.Benz, G.Georges. Abvance: Increasing Our Knowledge of Antibody Structural Space to Enable Faster and Better Decision Making in Antibody Drug Discovery To Be Published.