Sodium in PDB 6bcm: Structure of A Self-Inhibited N475A Variant of the Venezuelan Equine Encephalitis Virus (Veev) NSP2 Cysteine Protease

The structure of Structure of A Self-Inhibited N475A Variant of the Venezuelan Equine Encephalitis Virus (Veev) NSP2 Cysteine Protease, PDB code: 6bcm was solved by J.R.Compton, P.M.Legler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.46 / 2.10
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	42.527, 45.528, 47.765, 78.28, 65.31, 88.81
R / Rfree (%)	19.5 / 24.3

The binding sites of Sodium atom in the Structure of A Self-Inhibited N475A Variant of the Venezuelan Equine Encephalitis Virus (Veev) NSP2 Cysteine Protease (pdb code 6bcm). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Structure of A Self-Inhibited N475A Variant of the Venezuelan Equine Encephalitis Virus (Veev) NSP2 Cysteine Protease, PDB code: 6bcm:

Sodium binding site 1 out of 1 in the Structure of A Self-Inhibited N475A Variant of the Venezuelan Equine Encephalitis Virus (Veev) NSP2 Cysteine Protease


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structure of A Self-Inhibited N475A Variant of the Venezuelan Equine Encephalitis Virus (Veev) NSP2 Cysteine Protease within 5.0Å range: probe atom residue distance (Å) B Occ A:Na803 b:33.6 occ:1.00 O A:HOH1007 2.3 32.6 1.0 O A:ASP765 2.4 28.6 1.0 O A:LYS767 2.6 29.9 1.0 OD1 A:ASP765 3.1 22.6 1.0 N A:LYS767 3.2 35.3 1.0 C A:ASP765 3.3 27.1 1.0 C A:ARG766 3.4 36.6 1.0 CA A:ARG766 3.5 37.3 1.0 CA A:GLN739 3.5 24.5 1.0 C A:LYS767 3.6 32.6 1.0 N A:ARG766 3.7 32.1 1.0 NH1 A:ARG769 3.8 23.4 1.0 O A:GLN739 3.8 21.2 1.0 C A:GLN739 3.9 24.5 1.0 O A:ARG738 3.9 26.8 1.0 CA A:LYS767 3.9 36.0 1.0 O A:ARG766 4.2 40.3 1.0 CB A:GLN739 4.3 27.1 1.0 CG A:ASP765 4.3 24.8 1.0 N A:GLN739 4.4 26.8 1.0 C A:ARG738 4.5 25.8 1.0 CA A:ASP765 4.5 26.1 1.0 CG A:GLN739 4.6 26.1 1.0 CB A:LYS767 4.6 38.4 1.0 N A:ALA768 4.7 31.0 1.0 N A:ASP765 4.7 24.2 1.0 N A:PHE740 4.9 22.7 1.0 CB A:ARG766 4.9 41.3 1.0

J.R.Compton, M.J.Mickey, X.Hu, J.J.Marugan, P.M.Legler. Mutation of Asn-475 in the Venezuelan Equine Encephalitis Virus NSP2 Cysteine Protease Leads to A Self-Inhibited State. Biochemistry V. 56 6221 2017.
ISSN: ISSN 1520-4995
PubMed: 29064679
DOI: 10.1021/ACS.BIOCHEM.7B00746