Sodium in PDB 6amj: CAT192 Fab Wild Type

The structure of CAT192 Fab Wild Type, PDB code: 6amj was solved by D.M.Lord, R.R.Wei, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.71 / 2.49
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	55.950, 83.350, 104.910, 90.00, 104.77, 90.00
R / Rfree (%)	20.6 / 26.2

The binding sites of Sodium atom in the CAT192 Fab Wild Type (pdb code 6amj). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the CAT192 Fab Wild Type, PDB code: 6amj:

Sodium binding site 1 out of 1 in the CAT192 Fab Wild Type


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of CAT192 Fab Wild Type within 5.0Å range: probe atom residue distance (Å) B Occ H:Na302 b:47.5 occ:1.00 H42 H:PEG301 2.1 52.2 1.0 H11 H:PEG301 2.3 52.1 1.0 O H:PRO177 2.5 26.7 1.0 H41 H:PEG301 2.6 52.2 1.0 C4 H:PEG301 2.7 43.3 1.0 C1 H:PEG301 3.2 43.2 1.0 O H:SER187 3.2 29.2 1.0 CA H:LEU188 3.3 29.9 1.0 O1 H:PEG301 3.3 43.3 1.0 CG1 H:VAL179 3.5 25.8 1.0 O4 H:PEG301 3.5 43.5 1.0 OG L:SER162 3.5 28.3 1.0 C H:PRO177 3.5 26.6 1.0 CB L:SER162 3.6 27.4 1.0 CB H:LEU188 3.6 29.4 1.0 N H:VAL179 3.7 25.7 1.0 HO4 H:PEG301 3.7 52.4 1.0 H12 H:PEG301 3.7 52.1 1.0 CA H:ALA178 3.7 25.9 1.0 C H:ALA178 3.9 26.0 1.0 C3 H:PEG301 3.9 43.0 1.0 O2 H:PEG301 4.0 42.8 1.0 C H:SER187 4.1 30.3 1.0 N H:ALA178 4.1 26.1 1.0 CB H:PHE176 4.1 27.8 1.0 N H:LEU188 4.1 30.8 1.0 HO1 H:PEG301 4.1 52.1 1.0 O H:PHE176 4.2 29.0 1.0 C2 H:PEG301 4.2 42.9 1.0 N H:SER189 4.2 29.2 1.0 C H:LEU188 4.2 30.1 1.0 H32 H:PEG301 4.3 51.8 1.0 C H:PHE176 4.4 28.3 1.0 CB H:VAL179 4.4 26.0 1.0 CG2 H:VAL179 4.6 26.8 1.0 H31 H:PEG301 4.6 51.8 1.0 CA H:VAL179 4.6 25.7 1.0 O H:ALA178 4.7 26.4 1.0 N H:PRO177 4.7 27.9 1.0 H22 H:PEG301 4.7 51.7 1.0 CA H:PRO177 4.7 27.2 1.0 O H:HOH408 4.8 30.2 1.0 OG L:SER176 4.8 28.3 1.0 H21 H:PEG301 4.9 51.7 1.0 CA H:PHE176 4.9 28.5 1.0

D.M.Lord, J.J.Bird, D.M.Honey, A.Best, A.Park, R.R.Wei, H.Qiu. Structure-Based Engineering to Restore High Affinity Binding of An Isoform-Selective Anti-Tgf Beta 1 Antibody. Mabs V. 10 444 2018.
ISSN: ESSN 1942-0870
PubMed: 29333938
DOI: 10.1080/19420862.2018.1426421