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Sodium in PDB 5tnt: Discovery of Novel Aminobenzisoxazole Derivatives As Orally Available Factor Ixa Inhibitors
Enzymatic activity of Discovery of Novel Aminobenzisoxazole Derivatives As Orally Available Factor Ixa Inhibitors
All present enzymatic activity of Discovery of Novel Aminobenzisoxazole Derivatives As Orally Available Factor Ixa Inhibitors:
3.4.21.22;
3.4.21.22;
Protein crystallography data
The structure of Discovery of Novel Aminobenzisoxazole Derivatives As Orally Available Factor Ixa Inhibitors, PDB code: 5tnt
was solved by
I.Sakurada,
T.Endo,
K.Hikita,
T.Hirabayashi,
Y.Hosaka,
Y.Kato,
Y.Maeda,
S.Matsumoto,
T.Mizuno,
A.Nagasue,
T.Nishimura,
S.Shimada,
M.Shinozaki,
K.Taguchi,
K.Takeuchi,
T.Yokoyama,
A.Hruza,
P.Reichert,
T.Zhang,
H.B.Wood,
K.Nakao,
S.Furusako,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 20.50 / 1.40 |
| Space group | H 3 |
| Cell size a, b, c (Å), α, β, γ (°) | 99.084, 99.084, 94.680, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 14.6 / 16.1 |
Other elements in 5tnt:
The structure of Discovery of Novel Aminobenzisoxazole Derivatives As Orally Available Factor Ixa Inhibitors also contains other interesting chemical elements:
| Chlorine | (Cl) | 2 atoms |
Sodium Binding Sites:
The binding sites of Sodium atom in the Discovery of Novel Aminobenzisoxazole Derivatives As Orally Available Factor Ixa Inhibitors
(pdb code 5tnt). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Discovery of Novel Aminobenzisoxazole Derivatives As Orally Available Factor Ixa Inhibitors, PDB code: 5tnt:
In total only one binding site of Sodium was determined in the Discovery of Novel Aminobenzisoxazole Derivatives As Orally Available Factor Ixa Inhibitors, PDB code: 5tnt:
Sodium binding site 1 out of 1 in 5tnt
Go back to
Sodium Binding Sites List in 5tnt
Sodium binding site 1 out
of 1 in the Discovery of Novel Aminobenzisoxazole Derivatives As Orally Available Factor Ixa Inhibitors
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Sodium with other atoms in the Na binding
site number 1 of Discovery of Novel Aminobenzisoxazole Derivatives As Orally Available Factor Ixa Inhibitors within 5.0Å range:
|
Reference:
I.Sakurada,
T.Endo,
K.Hikita,
T.Hirabayashi,
Y.Hosaka,
Y.Kato,
Y.Maeda,
S.Matsumoto,
T.Mizuno,
H.Nagasue,
T.Nishimura,
S.Shimada,
M.Shinozaki,
K.Taguchi,
K.Takeuchi,
T.Yokoyama,
A.Hruza,
P.Reichert,
T.Zhang,
H.B.Wood,
K.Nakao,
S.Furusako.
Discovery of Novel Aminobenzisoxazole Derivatives As Orally Available Factor Ixa Inhibitors. Bioorg. Med. Chem. Lett. V. 27 2622 2017.
ISSN: ESSN 1464-3405
PubMed: 28408226
DOI: 10.1016/J.BMCL.2017.03.002
Page generated: Tue Dec 15 11:37:56 2020
ISSN: ESSN 1464-3405
PubMed: 28408226
DOI: 10.1016/J.BMCL.2017.03.002
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