Sodium in PDB 5tj8: Structure of WWP2 WW2-2,3-Linker-Hect (No WW2 Observed)

All present enzymatic activity of Structure of WWP2 WW2-2,3-Linker-Hect (No WW2 Observed):
2.3.2.26;

The structure of Structure of WWP2 WW2-2,3-Linker-Hect (No WW2 Observed), PDB code: 5tj8 was solved by Z.Chen, S.B.Gabelli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.30
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	44.229, 89.269, 111.474, 90.00, 90.00, 90.00
R / Rfree (%)	21.5 / 31.6

The binding sites of Sodium atom in the Structure of WWP2 WW2-2,3-Linker-Hect (No WW2 Observed) (pdb code 5tj8). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Structure of WWP2 WW2-2,3-Linker-Hect (No WW2 Observed), PDB code: 5tj8:

Sodium binding site 1 out of 1 in the Structure of WWP2 WW2-2,3-Linker-Hect (No WW2 Observed)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structure of WWP2 WW2-2,3-Linker-Hect (No WW2 Observed) within 5.0Å range: probe atom residue distance (Å) B Occ A:Na901 b:59.6 occ:1.00 OH A:TYR587 2.4 63.5 1.0 OD1 A:ASN840 2.5 49.6 1.0 O A:THR837 2.7 52.9 1.0 O A:THR799 2.7 45.4 1.0 CZ A:TYR587 3.5 62.4 1.0 CG A:ASN840 3.5 49.4 1.0 C A:THR799 3.6 42.0 1.0 CE1 A:TYR587 3.6 61.3 1.0 O A:ILE813 3.7 60.9 1.0 C A:THR837 3.8 56.5 1.0 CA A:THR799 3.8 41.3 1.0 ND2 A:ASN840 3.8 52.9 1.0 CB A:THR799 3.9 43.5 1.0 O A:HOH1015 4.0 40.4 1.0 CA A:THR837 4.6 49.8 1.0 CB A:THR837 4.6 52.1 1.0 N A:CYS838 4.7 56.0 0.5 N A:CYS838 4.7 61.9 0.5 OG1 A:THR799 4.8 41.6 1.0 CE2 A:TYR587 4.8 64.4 1.0 CA A:GLY814 4.8 61.8 1.0 CB A:ASN840 4.8 49.2 1.0 N A:GLY800 4.8 40.4 1.0 N A:ASN840 4.8 55.4 1.0 C A:ILE813 4.8 62.5 1.0 CA A:CYS838 4.8 56.7 0.5 CG2 A:THR799 4.8 41.0 1.0 CA A:CYS838 4.9 67.5 0.5 CD1 A:TYR587 5.0 65.0 1.0

Z.Chen, H.Jiang, W.Xu, X.Li, D.R.Dempsey, X.Zhang, P.Devreotes, C.Wolberger, L.M.Amzel, S.B.Gabelli, P.A.Cole. A Tunable Brake For Hect Ubiquitin Ligases. Mol. Cell V. 66 345 2017.
ISSN: ISSN 1097-4164
PubMed: 28475870
DOI: 10.1016/J.MOLCEL.2017.03.020