Sodium in PDB 5nwq: The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine.
Protein crystallography data
The structure of The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine., PDB code: 5nwq
was solved by
L.Huang,
J.Wang,
D.M.J.Lilley,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
41.80 /
1.91
|
Space group
|
P 31 2 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
83.604,
83.604,
66.594,
90.00,
90.00,
120.00
|
R / Rfree (%)
|
20.5 /
22.3
|
Other elements in 5nwq:
The structure of The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine. also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine.
(pdb code 5nwq). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 8 binding sites of Sodium where determined in the
The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine., PDB code: 5nwq:
Jump to Sodium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Sodium binding site 1 out
of 8 in 5nwq
Go back to
Sodium Binding Sites List in 5nwq
Sodium binding site 1 out
of 8 in the The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine.
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 1 of The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na103
b:0.7
occ:1.01
|
OP2
|
A:G9
|
2.5
|
46.2
|
1.0
|
H8
|
A:G9
|
2.6
|
48.4
|
1.0
|
O
|
A:HOH248
|
2.6
|
60.3
|
1.0
|
O
|
A:HOH221
|
2.8
|
40.5
|
1.0
|
O
|
A:HOH215
|
2.9
|
71.1
|
1.0
|
C8
|
A:G9
|
3.1
|
40.4
|
1.0
|
O5'
|
A:G9
|
3.2
|
41.6
|
1.0
|
NA
|
A:NA107
|
3.3
|
0.0
|
1.0
|
N7
|
A:G9
|
3.3
|
37.3
|
1.0
|
P
|
A:G9
|
3.4
|
44.4
|
1.0
|
H3'
|
A:G9
|
3.6
|
51.3
|
1.0
|
NA
|
A:NA108
|
4.0
|
0.1
|
1.0
|
OP2
|
A:G10
|
4.0
|
39.4
|
1.0
|
O
|
A:HOH230
|
4.1
|
52.8
|
1.0
|
H3'
|
A:A8
|
4.1
|
52.2
|
1.0
|
N9
|
A:G9
|
4.4
|
41.3
|
1.0
|
O2'
|
A:U11
|
4.4
|
43.5
|
1.0
|
OP1
|
A:G9
|
4.4
|
38.7
|
1.0
|
C5'
|
A:G9
|
4.5
|
51.4
|
1.0
|
C3'
|
A:G9
|
4.5
|
42.7
|
1.0
|
H2'
|
A:A8
|
4.6
|
48.8
|
1.0
|
C5
|
A:G9
|
4.6
|
38.7
|
1.0
|
O3'
|
A:A8
|
4.7
|
34.7
|
1.0
|
O
|
A:HOH234
|
4.7
|
45.7
|
1.0
|
C3'
|
A:A8
|
4.8
|
43.5
|
1.0
|
H5''
|
A:G9
|
4.9
|
61.6
|
1.0
|
C4'
|
A:G9
|
4.9
|
40.0
|
1.0
|
O4'
|
A:G9
|
4.9
|
44.1
|
1.0
|
N7
|
A:G10
|
4.9
|
42.8
|
1.0
|
O
|
A:HOH245
|
4.9
|
47.1
|
1.0
|
|
Sodium binding site 2 out
of 8 in 5nwq
Go back to
Sodium Binding Sites List in 5nwq
Sodium binding site 2 out
of 8 in the The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine.
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 2 of The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na104
b:44.8
occ:1.00
|
H62
|
A:A32
|
2.1
|
43.5
|
1.0
|
HO2'
|
A:G29
|
2.3
|
45.8
|
1.0
|
O2'
|
A:G29
|
2.6
|
38.2
|
1.0
|
OP2
|
A:A30
|
2.8
|
41.5
|
1.0
|
N6
|
A:A32
|
2.8
|
36.2
|
1.0
|
NA
|
A:NA106
|
2.8
|
45.6
|
1.0
|
H61
|
A:A32
|
3.0
|
43.5
|
1.0
|
O3'
|
A:G29
|
3.1
|
44.0
|
1.0
|
H1'
|
A:G29
|
3.1
|
46.0
|
1.0
|
P
|
A:A30
|
3.3
|
39.6
|
1.0
|
H61
|
A:A33
|
3.3
|
46.5
|
1.0
|
C2'
|
A:G29
|
3.5
|
39.0
|
1.0
|
NA
|
A:NA109
|
3.6
|
68.2
|
1.0
|
H41
|
A:C31
|
3.6
|
52.1
|
1.0
|
N6
|
A:A33
|
3.7
|
38.8
|
1.0
|
O
|
A:HOH231
|
3.7
|
40.5
|
1.0
|
H62
|
A:A33
|
3.7
|
46.5
|
1.0
|
C1'
|
A:G29
|
3.7
|
38.4
|
1.0
|
H1'
|
A:A5
|
3.8
|
46.1
|
1.0
|
OP1
|
A:A30
|
3.8
|
34.3
|
1.0
|
C3'
|
A:G29
|
3.8
|
32.2
|
1.0
|
MG
|
A:MG112
|
3.9
|
45.5
|
1.0
|
C6
|
A:A32
|
4.0
|
36.7
|
1.0
|
N4
|
A:C31
|
4.3
|
43.4
|
1.0
|
N7
|
A:A32
|
4.3
|
44.0
|
1.0
|
H2'
|
A:G29
|
4.3
|
46.8
|
1.0
|
H5
|
A:C31
|
4.3
|
49.7
|
1.0
|
N3
|
A:G29
|
4.4
|
36.3
|
1.0
|
H3'
|
A:G29
|
4.5
|
38.7
|
1.0
|
C5
|
A:A32
|
4.5
|
39.4
|
1.0
|
O2'
|
A:A5
|
4.5
|
34.5
|
1.0
|
NA
|
A:NA105
|
4.5
|
45.4
|
1.0
|
C6
|
A:A33
|
4.6
|
35.0
|
1.0
|
N9
|
A:G29
|
4.6
|
35.7
|
1.0
|
N3
|
A:A5
|
4.7
|
38.5
|
1.0
|
H42
|
A:C31
|
4.7
|
52.1
|
1.0
|
C1'
|
A:A5
|
4.7
|
38.4
|
1.0
|
O4'
|
A:G29
|
4.8
|
40.7
|
1.0
|
O5'
|
A:A30
|
4.8
|
49.7
|
1.0
|
C4
|
A:G29
|
4.8
|
41.3
|
1.0
|
O
|
A:HOH204
|
4.9
|
37.6
|
1.0
|
C4'
|
A:G29
|
4.9
|
40.4
|
1.0
|
C5
|
A:C31
|
4.9
|
41.5
|
1.0
|
H4'
|
A:A5
|
5.0
|
39.8
|
1.0
|
C4
|
A:C31
|
5.0
|
48.4
|
1.0
|
|
Sodium binding site 3 out
of 8 in 5nwq
Go back to
Sodium Binding Sites List in 5nwq
Sodium binding site 3 out
of 8 in the The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine.
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 3 of The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na105
b:45.4
occ:1.00
|
O6
|
A:G34
|
2.7
|
38.4
|
1.0
|
O2
|
A:C6
|
2.9
|
36.9
|
1.0
|
O
|
A:HOH247
|
3.0
|
42.5
|
1.0
|
NA
|
A:NA106
|
3.0
|
45.6
|
1.0
|
O4'
|
A:C6
|
3.1
|
38.5
|
1.0
|
H1'
|
A:C6
|
3.2
|
40.7
|
1.0
|
H1
|
A:G34
|
3.3
|
39.2
|
1.0
|
H4'
|
A:C6
|
3.5
|
50.9
|
1.0
|
C6
|
A:G34
|
3.6
|
31.9
|
1.0
|
O4'
|
A:G7
|
3.6
|
41.1
|
1.0
|
C1'
|
A:C6
|
3.7
|
33.9
|
1.0
|
HO2'
|
A:A5
|
3.7
|
41.3
|
1.0
|
O2'
|
A:A5
|
3.7
|
34.5
|
1.0
|
NA
|
A:NA109
|
3.8
|
68.2
|
1.0
|
N1
|
A:G34
|
3.8
|
32.6
|
1.0
|
C4'
|
A:C6
|
3.9
|
42.4
|
1.0
|
H8
|
A:G7
|
3.9
|
35.9
|
1.0
|
H61
|
A:A33
|
3.9
|
46.5
|
1.0
|
C2
|
A:C6
|
3.9
|
34.5
|
1.0
|
C8
|
A:G7
|
4.0
|
29.9
|
1.0
|
H1'
|
A:G7
|
4.1
|
51.3
|
1.0
|
N9
|
A:G7
|
4.2
|
35.1
|
1.0
|
C1'
|
A:G7
|
4.2
|
42.8
|
1.0
|
N1
|
A:C6
|
4.3
|
35.5
|
1.0
|
O3'
|
A:C6
|
4.3
|
43.7
|
1.0
|
H5'
|
A:G7
|
4.5
|
50.0
|
1.0
|
H62
|
A:A33
|
4.5
|
46.5
|
1.0
|
N6
|
A:A33
|
4.5
|
38.8
|
1.0
|
NA
|
A:NA104
|
4.5
|
44.8
|
1.0
|
C3'
|
A:C6
|
4.7
|
35.4
|
1.0
|
N7
|
A:G7
|
4.7
|
34.0
|
1.0
|
H5'
|
A:C6
|
4.8
|
45.7
|
1.0
|
C4'
|
A:G7
|
4.9
|
42.0
|
1.0
|
C5
|
A:G34
|
4.9
|
41.9
|
1.0
|
C2'
|
A:C6
|
4.9
|
42.6
|
1.0
|
C4
|
A:G7
|
4.9
|
41.8
|
1.0
|
H1'
|
A:A5
|
4.9
|
46.1
|
1.0
|
C2'
|
A:A5
|
5.0
|
37.9
|
1.0
|
C5'
|
A:C6
|
5.0
|
38.1
|
1.0
|
|
Sodium binding site 4 out
of 8 in 5nwq
Go back to
Sodium Binding Sites List in 5nwq
Sodium binding site 4 out
of 8 in the The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine.
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 4 of The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na106
b:45.6
occ:1.00
|
H61
|
A:A33
|
2.1
|
46.5
|
1.0
|
N3
|
A:A5
|
2.7
|
38.5
|
1.0
|
NA
|
A:NA104
|
2.8
|
44.8
|
1.0
|
N6
|
A:A33
|
2.9
|
38.8
|
1.0
|
H1'
|
A:A5
|
3.0
|
46.1
|
1.0
|
NA
|
A:NA105
|
3.0
|
45.4
|
1.0
|
H2
|
A:A5
|
3.2
|
46.5
|
1.0
|
H1
|
A:G34
|
3.2
|
39.2
|
1.0
|
H62
|
A:A33
|
3.4
|
46.5
|
1.0
|
C2
|
A:A5
|
3.4
|
38.7
|
1.0
|
N1
|
A:G34
|
3.4
|
32.6
|
1.0
|
O2
|
A:C6
|
3.5
|
36.9
|
1.0
|
O2'
|
A:A5
|
3.5
|
34.5
|
1.0
|
O6
|
A:G34
|
3.6
|
38.4
|
1.0
|
C6
|
A:G34
|
3.7
|
31.9
|
1.0
|
H61
|
A:A32
|
3.8
|
43.5
|
1.0
|
H62
|
A:A32
|
3.8
|
43.5
|
1.0
|
C6
|
A:A33
|
3.8
|
35.0
|
1.0
|
N1
|
A:A33
|
3.8
|
37.2
|
1.0
|
C1'
|
A:A5
|
3.8
|
38.4
|
1.0
|
C4
|
A:A5
|
3.8
|
38.4
|
1.0
|
O2'
|
A:G29
|
3.9
|
38.2
|
1.0
|
HO2'
|
A:G29
|
3.9
|
45.8
|
1.0
|
N6
|
A:A32
|
4.0
|
36.2
|
1.0
|
HO2'
|
A:A5
|
4.1
|
41.3
|
1.0
|
C2
|
A:C6
|
4.1
|
34.5
|
1.0
|
NA
|
A:NA109
|
4.1
|
68.2
|
1.0
|
C2
|
A:G34
|
4.2
|
33.7
|
1.0
|
C2'
|
A:A5
|
4.2
|
37.9
|
1.0
|
N9
|
A:A5
|
4.3
|
36.8
|
1.0
|
H21
|
A:G34
|
4.3
|
43.7
|
1.0
|
H2'
|
A:A5
|
4.5
|
45.5
|
1.0
|
N3
|
A:C6
|
4.5
|
31.9
|
1.0
|
N2
|
A:G34
|
4.5
|
36.4
|
1.0
|
C5
|
A:G34
|
4.6
|
41.9
|
1.0
|
O4'
|
A:C6
|
4.7
|
38.5
|
1.0
|
N1
|
A:A5
|
4.7
|
40.5
|
1.0
|
N3
|
A:G29
|
4.8
|
36.3
|
1.0
|
H1'
|
A:G29
|
4.8
|
46.0
|
1.0
|
O4'
|
A:A5
|
4.9
|
38.3
|
1.0
|
N3
|
A:G34
|
5.0
|
35.0
|
1.0
|
N1
|
A:C6
|
5.0
|
35.5
|
1.0
|
|
Sodium binding site 5 out
of 8 in 5nwq
Go back to
Sodium Binding Sites List in 5nwq
Sodium binding site 5 out
of 8 in the The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine.
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 5 of The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na107
b:0.0
occ:1.00
|
O
|
A:HOH215
|
2.3
|
71.1
|
1.0
|
O
|
A:HOH234
|
3.2
|
45.7
|
1.0
|
NA
|
A:NA103
|
3.3
|
0.7
|
1.0
|
O
|
A:HOH245
|
3.3
|
47.1
|
1.0
|
O
|
A:HOH221
|
3.4
|
40.5
|
1.0
|
O
|
A:HOH248
|
3.7
|
60.3
|
1.0
|
K
|
A:K102
|
3.8
|
76.7
|
1.0
|
NA
|
A:NA108
|
4.2
|
0.1
|
1.0
|
O
|
A:HOH210
|
4.4
|
57.9
|
1.0
|
N7
|
A:G9
|
4.7
|
37.3
|
1.0
|
OP2
|
A:G9
|
4.7
|
46.2
|
1.0
|
|
Sodium binding site 6 out
of 8 in 5nwq
Go back to
Sodium Binding Sites List in 5nwq
Sodium binding site 6 out
of 8 in the The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine.
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 6 of The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na108
b:0.1
occ:1.00
|
O
|
A:HOH248
|
2.3
|
60.3
|
1.0
|
O
|
A:HOH221
|
2.3
|
40.5
|
1.0
|
O
|
A:HOH214
|
2.4
|
59.6
|
1.0
|
O
|
A:HOH245
|
2.4
|
47.1
|
1.0
|
O2
|
A:U11
|
2.4
|
40.4
|
1.0
|
O2'
|
A:U11
|
2.5
|
43.5
|
1.0
|
H1'
|
A:U11
|
2.8
|
55.1
|
1.0
|
C2
|
A:U11
|
3.3
|
36.1
|
1.0
|
C1'
|
A:U11
|
3.4
|
45.9
|
1.0
|
C2'
|
A:U11
|
3.4
|
43.0
|
1.0
|
K
|
A:K102
|
3.5
|
76.7
|
1.0
|
H5
|
A:C13
|
3.7
|
48.9
|
1.0
|
N1
|
A:U11
|
3.8
|
44.6
|
1.0
|
O3'
|
A:U11
|
3.9
|
43.0
|
1.0
|
NA
|
A:NA103
|
4.0
|
0.7
|
1.0
|
N7
|
A:G10
|
4.1
|
42.8
|
1.0
|
H2'
|
A:U11
|
4.1
|
51.5
|
1.0
|
H41
|
A:C13
|
4.2
|
46.6
|
1.0
|
NA
|
A:NA107
|
4.2
|
0.0
|
1.0
|
C3'
|
A:U11
|
4.4
|
41.2
|
1.0
|
N3
|
A:U11
|
4.4
|
38.5
|
1.0
|
O
|
A:HOH230
|
4.4
|
52.8
|
1.0
|
OP2
|
A:C13
|
4.5
|
51.4
|
1.0
|
H3
|
A:U11
|
4.5
|
46.2
|
1.0
|
C5
|
A:C13
|
4.5
|
40.8
|
1.0
|
H8
|
A:G10
|
4.5
|
44.5
|
1.0
|
OP2
|
A:G10
|
4.6
|
39.4
|
1.0
|
O
|
A:HOH210
|
4.6
|
57.9
|
1.0
|
O4'
|
A:U11
|
4.7
|
43.7
|
1.0
|
C8
|
A:G10
|
4.7
|
37.1
|
1.0
|
N4
|
A:C13
|
4.8
|
38.8
|
1.0
|
N7
|
A:G14
|
4.9
|
34.9
|
1.0
|
|
Sodium binding site 7 out
of 8 in 5nwq
Go back to
Sodium Binding Sites List in 5nwq
Sodium binding site 7 out
of 8 in the The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine.
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 7 of The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na109
b:68.2
occ:1.00
|
HO2'
|
A:G29
|
2.5
|
45.8
|
1.0
|
O2'
|
A:A5
|
2.6
|
34.5
|
1.0
|
HO2'
|
A:A5
|
2.7
|
41.3
|
1.0
|
OP1
|
A:A30
|
2.7
|
34.3
|
1.0
|
O2'
|
A:G29
|
3.0
|
38.2
|
1.0
|
H5'
|
A:C6
|
3.1
|
45.7
|
1.0
|
H4'
|
A:A5
|
3.4
|
39.8
|
1.0
|
NA
|
A:NA104
|
3.6
|
44.8
|
1.0
|
P
|
A:A30
|
3.7
|
39.6
|
1.0
|
H4'
|
A:C6
|
3.8
|
50.9
|
1.0
|
NA
|
A:NA105
|
3.8
|
45.4
|
1.0
|
C2'
|
A:A5
|
3.8
|
37.9
|
1.0
|
O3'
|
A:A5
|
3.8
|
40.4
|
1.0
|
O4'
|
A:C6
|
3.8
|
38.5
|
1.0
|
H1'
|
A:A5
|
3.9
|
46.1
|
1.0
|
OP2
|
A:A30
|
3.9
|
41.5
|
1.0
|
C5'
|
A:C6
|
4.0
|
38.1
|
1.0
|
C4'
|
A:C6
|
4.1
|
42.4
|
1.0
|
C4'
|
A:A5
|
4.1
|
33.1
|
1.0
|
NA
|
A:NA106
|
4.1
|
45.6
|
1.0
|
C3'
|
A:A5
|
4.1
|
36.5
|
1.0
|
C2'
|
A:G29
|
4.2
|
39.0
|
1.0
|
O
|
A:HOH204
|
4.3
|
37.6
|
1.0
|
C1'
|
A:A5
|
4.3
|
38.4
|
1.0
|
O3'
|
A:G29
|
4.4
|
44.0
|
1.0
|
H3'
|
A:G29
|
4.4
|
38.7
|
1.0
|
H2'
|
A:G29
|
4.5
|
46.8
|
1.0
|
O
|
A:HOH247
|
4.5
|
42.5
|
1.0
|
H2'
|
A:A5
|
4.5
|
45.5
|
1.0
|
C3'
|
A:G29
|
4.6
|
32.2
|
1.0
|
O4'
|
A:A5
|
4.6
|
38.3
|
1.0
|
H5''
|
A:C6
|
4.6
|
45.7
|
1.0
|
O5'
|
A:C6
|
4.7
|
37.7
|
1.0
|
MG
|
A:MG112
|
4.7
|
45.5
|
1.0
|
P
|
A:C6
|
5.0
|
43.0
|
1.0
|
|
Sodium binding site 8 out
of 8 in 5nwq
Go back to
Sodium Binding Sites List in 5nwq
Sodium binding site 8 out
of 8 in the The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine.
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 8 of The Structure of the Thermobifida Fusca Guanidine III Riboswitch with Guanidine. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Na102
b:0.6
occ:1.01
|
O2
|
B:U11
|
3.8
|
48.0
|
1.0
|
O2'
|
B:U11
|
3.9
|
51.3
|
1.0
|
HO2'
|
B:U11
|
4.1
|
61.5
|
1.0
|
N7
|
B:G10
|
4.4
|
74.8
|
1.0
|
N7
|
B:G9
|
4.5
|
77.4
|
1.0
|
C2
|
B:U11
|
4.7
|
51.3
|
1.0
|
N7
|
B:G14
|
4.7
|
60.3
|
1.0
|
H1'
|
B:U11
|
4.8
|
68.5
|
1.0
|
H8
|
B:G9
|
4.9
|
0.4
|
1.0
|
OP2
|
B:G9
|
4.9
|
91.2
|
1.0
|
OP2
|
B:C13
|
4.9
|
62.3
|
1.0
|
O6
|
B:G10
|
4.9
|
64.1
|
1.0
|
H5
|
B:C13
|
4.9
|
65.7
|
1.0
|
|
Reference:
L.Huang,
J.Wang,
T.J.Wilson,
D.M.J.Lilley.
Structure of the Guanidine III Riboswitch. Cell Chem Biol V. 24 1407 2017.
ISSN: ESSN 2451-9456
PubMed: 28988949
DOI: 10.1016/J.CHEMBIOL.2017.08.021
Page generated: Mon Oct 7 23:03:38 2024
|