Sodium in PDB 5m5j: Thioredoxin Reductase From Giardia Duodenalis

All present enzymatic activity of Thioredoxin Reductase From Giardia Duodenalis:
1.8.1.9;

The structure of Thioredoxin Reductase From Giardia Duodenalis, PDB code: 5m5j was solved by A.Fiorillo, A.Ilari, M.Lalle, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.60 / 2.65
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	85.643, 85.643, 163.221, 90.00, 90.00, 90.00
R / Rfree (%)	20.2 / 26

The binding sites of Sodium atom in the Thioredoxin Reductase From Giardia Duodenalis (pdb code 5m5j). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Thioredoxin Reductase From Giardia Duodenalis, PDB code: 5m5j:

Sodium binding site 1 out of 1 in the Thioredoxin Reductase From Giardia Duodenalis


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Thioredoxin Reductase From Giardia Duodenalis within 5.0Å range: probe atom residue distance (Å) B Occ B:Na1002 b:41.9 occ:1.00 OE2 B:GLU82 2.7 30.1 1.0 OE2 B:GLU103 2.8 34.7 1.0 CD B:GLU82 3.6 31.4 1.0 NH2 B:ARG5 3.7 31.9 1.0 CD B:GLU103 3.7 34.9 1.0 OE1 B:GLU82 3.8 31.2 1.0 NH1 B:ARG5 3.9 32.8 1.0 OE1 B:GLU103 3.9 36.3 1.0 CZ B:ARG5 4.3 32.5 1.0 CE1 B:HIS98 4.3 24.9 1.0 CD2 B:LEU80 4.3 29.5 1.0 ND1 B:HIS98 4.9 24.3 1.0

S.Brogi, A.Fiorillo, G.Chemi, S.Butini, M.Lalle, A.Ilari, S.Gemma, G.Campiani. Structural Characterization of Giardia Duodenalis Thioredoxin Reductase (Gtrxr) and Computational Analysis of Its Interaction with Nbdhex. Eur J Med Chem V. 135 479 2017.
ISSN: ISSN 1768-3254
PubMed: 28477573
DOI: 10.1016/J.EJMECH.2017.04.057