Sodium in PDB 5hjg: Crystal Structure of Human Transthyretin in Complex with Tetrabromobisphenol A (Tbbpa)

The structure of Crystal Structure of Human Transthyretin in Complex with Tetrabromobisphenol A (Tbbpa), PDB code: 5hjg was solved by A.Begum, I.Iakovleva, K.Brannstrom, J.Zhang, P.Andersson, A.Olofsson, A.E.Sauer-Eriksson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.65 / 1.40
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	42.358, 85.298, 63.186, 90.00, 90.00, 90.00
R / Rfree (%)	14.5 / 18.2

The structure of Crystal Structure of Human Transthyretin in Complex with Tetrabromobisphenol A (Tbbpa) also contains other interesting chemical elements:

Bromine

(Br)

8 atoms

The binding sites of Sodium atom in the Crystal Structure of Human Transthyretin in Complex with Tetrabromobisphenol A (Tbbpa) (pdb code 5hjg). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Human Transthyretin in Complex with Tetrabromobisphenol A (Tbbpa), PDB code: 5hjg:

Sodium binding site 1 out of 1 in the Crystal Structure of Human Transthyretin in Complex with Tetrabromobisphenol A (Tbbpa)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Human Transthyretin in Complex with Tetrabromobisphenol A (Tbbpa) within 5.0Å range: probe atom residue distance (Å) B Occ A:Na202 b:18.5 occ:1.00 O A:ASP99 2.2 29.7 1.0 O A:HOH311 2.3 34.8 1.0 O A:HOH385 2.3 49.5 1.0 C A:ASP99 3.4 28.8 1.0 HB2 A:ASP99 3.5 38.3 1.0 HA A:SER100 3.8 38.2 1.0 OE2 A:GLU66 4.0 27.6 1.0 HA A:ASP99 4.0 34.0 1.0 CA A:ASP99 4.1 28.3 1.0 O A:HOH388 4.1 42.0 1.0 CB A:ASP99 4.3 31.9 1.0 N A:SER100 4.4 29.1 1.0 CA A:SER100 4.5 31.8 1.0 CD A:GLU66 4.5 25.3 1.0 OE1 A:GLU66 4.7 25.8 1.0 HB3 A:ASP99 4.9 38.3 1.0 OG A:SER100 4.9 39.9 1.0

I.Iakovleva, A.Begum, K.Brannstrom, A.Wijsekera, L.Nilsson, J.Zhang, P.L.Andersson, A.E.Sauer-Eriksson, A.Olofsson. Tetrabromobisphenol A Is An Efficient Stabilizer of the Transthyretin Tetramer. Plos One V. 11 53529 2016.
ISSN: ESSN 1932-6203
PubMed: 27093678
DOI: 10.1371/JOURNAL.PONE.0153529