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Atomistry » Sodium » PDB 5g3g-5gwa » 5ghn | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 5g3g-5gwa » 5ghn » |
Sodium in PDB 5ghn: Crystal Structure of Human MTH1(G2K/D120N Mutant) in Complex with 2- Oxo-DatpEnzymatic activity of Crystal Structure of Human MTH1(G2K/D120N Mutant) in Complex with 2- Oxo-Datp
All present enzymatic activity of Crystal Structure of Human MTH1(G2K/D120N Mutant) in Complex with 2- Oxo-Datp:
3.6.1.55; 3.6.1.56; Protein crystallography data
The structure of Crystal Structure of Human MTH1(G2K/D120N Mutant) in Complex with 2- Oxo-Datp, PDB code: 5ghn
was solved by
T.Nakamura,
S.Waz,
K.Hirata,
Y.Nakabeppu,
Y.Yamagata,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Sodium Binding Sites:
The binding sites of Sodium atom in the Crystal Structure of Human MTH1(G2K/D120N Mutant) in Complex with 2- Oxo-Datp
(pdb code 5ghn). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Crystal Structure of Human MTH1(G2K/D120N Mutant) in Complex with 2- Oxo-Datp, PDB code: 5ghn: Jump to Sodium binding site number: 1; 2; 3; Sodium binding site 1 out of 3 in 5ghnGo back to Sodium Binding Sites List in 5ghn
Sodium binding site 1 out
of 3 in the Crystal Structure of Human MTH1(G2K/D120N Mutant) in Complex with 2- Oxo-Datp
Mono view Stereo pair view
Sodium binding site 2 out of 3 in 5ghnGo back to Sodium Binding Sites List in 5ghn
Sodium binding site 2 out
of 3 in the Crystal Structure of Human MTH1(G2K/D120N Mutant) in Complex with 2- Oxo-Datp
Mono view Stereo pair view
Sodium binding site 3 out of 3 in 5ghnGo back to Sodium Binding Sites List in 5ghn
Sodium binding site 3 out
of 3 in the Crystal Structure of Human MTH1(G2K/D120N Mutant) in Complex with 2- Oxo-Datp
Mono view Stereo pair view
Reference:
S.Waz,
T.Nakamura,
K.Hirata,
Y.Koga-Ogawa,
M.Chirifu,
T.Arimori,
T.Tamada,
S.Ikemizu,
Y.Nakabeppu,
Y.Yamagata.
Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism For Its Broad Substrate Specificity J. Biol. Chem. V. 292 2785 2017.
Page generated: Mon Oct 7 21:10:48 2024
ISSN: ESSN 1083-351X PubMed: 28035004 DOI: 10.1074/JBC.M116.749713 |
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