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Sodium in PDB 5egm: Development of A Novel Tricyclic Class of Potent and Selective Fixa Inhibitors
Enzymatic activity of Development of A Novel Tricyclic Class of Potent and Selective Fixa Inhibitors
All present enzymatic activity of Development of A Novel Tricyclic Class of Potent and Selective Fixa Inhibitors:
3.4.21.22;
3.4.21.22;
Protein crystallography data
The structure of Development of A Novel Tricyclic Class of Potent and Selective Fixa Inhibitors, PDB code: 5egm
was solved by
D.Meng,
P.Andre,
T.J.Bateman,
R.Berger,
Y.Chen,
K.Desai,
S.Dewnani,
K.Ellsworth,
D.Feng,
W.M.Geissler,
L.Guo,
A.Hruza,
T.Jian,
H.Li,
D.L.Parker,
P.Reichert,
E.C.Sherer,
C.J.Smith,
L.M.Sonatore,
R.Tschirret-Guth,
J.Wu,
J.Xu,
T.Zhang,
L.Campeau,
R.Orr,
M.Poirier,
J.Mccabe-Dunn,
K.Araki,
T.Nishimura,
I.Sakurada,
T.Hirabayashi,
H.B.Wood,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 23.25 / 1.84 |
| Space group | H 3 |
| Cell size a, b, c (Å), α, β, γ (°) | 99.298, 99.298, 94.685, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 14.8 / 17.1 |
Other elements in 5egm:
The structure of Development of A Novel Tricyclic Class of Potent and Selective Fixa Inhibitors also contains other interesting chemical elements:
| Chlorine | (Cl) | 1 atom |
Sodium Binding Sites:
The binding sites of Sodium atom in the Development of A Novel Tricyclic Class of Potent and Selective Fixa Inhibitors
(pdb code 5egm). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Development of A Novel Tricyclic Class of Potent and Selective Fixa Inhibitors, PDB code: 5egm:
In total only one binding site of Sodium was determined in the Development of A Novel Tricyclic Class of Potent and Selective Fixa Inhibitors, PDB code: 5egm:
Sodium binding site 1 out of 1 in 5egm
Go back to
Sodium Binding Sites List in 5egm
Sodium binding site 1 out
of 1 in the Development of A Novel Tricyclic Class of Potent and Selective Fixa Inhibitors
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Sodium with other atoms in the Na binding
site number 1 of Development of A Novel Tricyclic Class of Potent and Selective Fixa Inhibitors within 5.0Å range:
|
Reference:
D.Meng,
P.Andre,
T.J.Bateman,
R.Berger,
Y.H.Chen,
K.Desai,
S.Dewnani,
K.Ellsworth,
D.Feng,
W.M.Geissler,
L.Guo,
A.Hruza,
T.Jian,
H.Li,
J.Metzger,
D.L.Parker,
P.Reichert,
E.C.Sherer,
C.J.Smith,
L.M.Sonatore,
R.Tschirret-Guth,
J.Wu,
J.Xu,
T.Zhang,
L.C.Campeau,
R.Orr,
M.Poirier,
J.Mccabe-Dunn,
K.Araki,
T.Nishimura,
I.Sakurada,
T.Hirabayashi,
H.B.Wood.
Development of A Novel Tricyclic Class of Potent and Selective Fixa Inhibitors. Bioorg.Med.Chem.Lett. V. 25 5437 2015.
ISSN: ESSN 1464-3405
PubMed: 26318999
DOI: 10.1016/J.BMCL.2015.07.078
Page generated: Tue Dec 15 10:56:18 2020
ISSN: ESSN 1464-3405
PubMed: 26318999
DOI: 10.1016/J.BMCL.2015.07.078
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