Sodium in PDB 4x8a: Navms Pore and C-Terminal Domain Grown From Protein Purified in Licl

The structure of Navms Pore and C-Terminal Domain Grown From Protein Purified in Licl, PDB code: 4x8a was solved by C.E.Naylor, C.Bagneris, B.A.Wallace, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.56 / 3.02
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	80.090, 332.350, 80.090, 90.00, 90.00, 90.00
R / Rfree (%)	21.7 / 24.4

The binding sites of Sodium atom in the Navms Pore and C-Terminal Domain Grown From Protein Purified in Licl (pdb code 4x8a). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 5 binding sites of Sodium where determined in the Navms Pore and C-Terminal Domain Grown From Protein Purified in Licl, PDB code: 4x8a:
Jump to Sodium binding site number: 1; 2; 3; 4; 5;

Sodium binding site 1 out of 5 in the Navms Pore and C-Terminal Domain Grown From Protein Purified in Licl


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Navms Pore and C-Terminal Domain Grown From Protein Purified in Licl within 5.0Å range: probe atom residue distance (Å) B Occ A:Na303 b:52.7 occ:0.50 OG A:SER179 4.1 43.1 1.0 OG B:SER179 4.1 45.1 1.0 OE1 A:GLU178 4.2 48.3 1.0 OE1 B:GLU178 4.3 33.9 1.0 N B:SER179 4.8 27.9 1.0 N A:SER179 4.8 27.4 1.0

Sodium binding site 2 out of 5 in the Navms Pore and C-Terminal Domain Grown From Protein Purified in Licl


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Navms Pore and C-Terminal Domain Grown From Protein Purified in Licl within 5.0Å range: probe atom residue distance (Å) B Occ A:Na304 b:37.9 occ:0.50 NA A:NA305 3.0 30.4 0.5 O A:LEU177 4.9 30.7 1.0 O B:LEU177 4.9 32.1 1.0

Sodium binding site 3 out of 5 in the Navms Pore and C-Terminal Domain Grown From Protein Purified in Licl


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Navms Pore and C-Terminal Domain Grown From Protein Purified in Licl within 5.0Å range: probe atom residue distance (Å) B Occ A:Na305 b:30.4 occ:0.50 NA A:NA304 3.0 37.9 0.5 O B:THR176 4.8 35.4 1.0 O A:THR176 4.8 36.5 1.0

Sodium binding site 4 out of 5 in the Navms Pore and C-Terminal Domain Grown From Protein Purified in Licl


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 4 of Navms Pore and C-Terminal Domain Grown From Protein Purified in Licl within 5.0Å range: probe atom residue distance (Å) B Occ C:Na302 b:38.3 occ:0.50 N D:SER179 4.5 30.1 1.0 N C:SER179 4.5 31.3 1.0 OE1 C:GLU178 4.5 45.1 1.0 OE1 D:GLU178 4.6 42.0 1.0 CA D:GLU178 4.9 25.4 1.0 CA C:GLU178 5.0 28.7 1.0

Sodium binding site 5 out of 5 in the Navms Pore and C-Terminal Domain Grown From Protein Purified in Licl


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 5 of Navms Pore and C-Terminal Domain Grown From Protein Purified in Licl within 5.0Å range: probe atom residue distance (Å) B Occ C:Na303 b:26.6 occ:0.50 O C:THR176 4.6 37.6 1.0 O D:THR176 4.7 36.0 1.0

C.E.Naylor, C.Bagneris, P.G.Decaen, A.Sula, A.Scaglione, D.E.Clapham, B.A.Wallace. Molecular Basis of Ion Permeability in A Voltage-Gated Sodium Channel. Embo J. V. 35 820 2016.
ISSN: ESSN 1460-2075
PubMed: 26873592
DOI: 10.15252/EMBJ.201593285