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Atomistry » Sodium » PDB 4wcn-4wxq » 4wnw » |
Sodium in PDB 4wnw: Human Cytochrome P450 2D6 Thioridazine ComplexEnzymatic activity of Human Cytochrome P450 2D6 Thioridazine Complex
All present enzymatic activity of Human Cytochrome P450 2D6 Thioridazine Complex:
1.14.14.1; Protein crystallography data
The structure of Human Cytochrome P450 2D6 Thioridazine Complex, PDB code: 4wnw
was solved by
A.Wang,
C.D.Stout,
E.F.Johnson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4wnw:
The structure of Human Cytochrome P450 2D6 Thioridazine Complex also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Human Cytochrome P450 2D6 Thioridazine Complex
(pdb code 4wnw). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Human Cytochrome P450 2D6 Thioridazine Complex, PDB code: 4wnw: Jump to Sodium binding site number: 1; 2; Sodium binding site 1 out of 2 in 4wnwGo back to![]() ![]()
Sodium binding site 1 out
of 2 in the Human Cytochrome P450 2D6 Thioridazine Complex
![]() Mono view ![]() Stereo pair view
Sodium binding site 2 out of 2 in 4wnwGo back to![]() ![]()
Sodium binding site 2 out
of 2 in the Human Cytochrome P450 2D6 Thioridazine Complex
![]() Mono view ![]() Stereo pair view
Reference:
A.Wang,
C.D.Stout,
Q.Zhang,
E.F.Johnson.
Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6)Substrate and Inhibitor Binding. J.Biol.Chem. 2015.
Page generated: Tue Dec 15 09:38:35 2020
ISSN: ESSN 1083-351X PubMed: 25555909 DOI: 10.1074/JBC.M114.627661 |
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