Sodium in PDB 4wfz: Coxsackievirus B3 3DPOL Rna Dependent Rna Polymerase - Nacl Crystal Form

All present enzymatic activity of Coxsackievirus B3 3DPOL Rna Dependent Rna Polymerase - Nacl Crystal Form:
2.7.7.48;

The structure of Coxsackievirus B3 3DPOL Rna Dependent Rna Polymerase - Nacl Crystal Form, PDB code: 4wfz was solved by O.B.Peersen, S.M.Mcdonald, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	58.88 / 1.80
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	74.423, 74.423, 288.757, 90.00, 90.00, 90.00
R / Rfree (%)	20 / 23.1

The binding sites of Sodium atom in the Coxsackievirus B3 3DPOL Rna Dependent Rna Polymerase - Nacl Crystal Form (pdb code 4wfz). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Coxsackievirus B3 3DPOL Rna Dependent Rna Polymerase - Nacl Crystal Form, PDB code: 4wfz:

Sodium binding site 1 out of 1 in the Coxsackievirus B3 3DPOL Rna Dependent Rna Polymerase - Nacl Crystal Form


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Coxsackievirus B3 3DPOL Rna Dependent Rna Polymerase - Nacl Crystal Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Na501 b:24.8 occ:1.00 O A:GLY286 2.5 22.4 1.0 O A:LEU269 2.5 23.5 1.0 O A:HOH731 2.5 27.4 1.0 O A:GLY285 2.5 22.6 1.0 O A:CYS270 2.6 24.5 1.0 OG A:SER272 2.6 24.1 1.0 C A:CYS270 3.3 26.1 1.0 C A:GLY285 3.4 23.2 1.0 C A:GLY286 3.5 24.0 1.0 C A:LEU269 3.6 23.7 1.0 CB A:SER272 3.6 25.7 1.0 CA A:CYS270 3.8 23.2 1.0 CA A:GLY286 4.0 22.4 1.0 N A:GLY286 4.1 23.0 1.0 N A:CYS270 4.1 23.5 1.0 N A:SER272 4.2 25.8 1.0 CD A:PRO288 4.2 25.2 1.0 O A:VAL283 4.2 27.8 1.0 N A:ASN271 4.3 25.2 1.0 CG1 A:VAL283 4.4 24.2 1.0 N A:GLY285 4.4 25.1 1.0 CA A:GLY285 4.4 25.8 1.0 CB A:VAL283 4.4 26.5 1.0 CA A:SER272 4.6 26.9 1.0 N A:PRO288 4.6 24.9 1.0 CG A:PRO288 4.6 28.3 1.0 N A:MET287 4.7 22.4 1.0 NE2 A:HIS274 4.7 26.8 1.0 CA A:ASN271 4.7 28.1 1.0 C A:VAL283 4.8 25.0 1.0 C A:ASN271 4.9 25.3 1.0 CA A:LEU269 4.9 24.5 1.0 CB A:PRO288 4.9 27.9 1.0 CA A:MET287 5.0 22.4 1.0

G.Campagnola, S.Mcdonald, S.Beaucourt, M.Vignuzzi, O.B.Peersen. Structure-Function Relationships Underlying the Replication Fidelity of Viral Rna-Dependent Rna Polymerases. J.Virol. 2014.
ISSN: ESSN 1098-5514
PubMed: 25320316
DOI: 10.1128/JVI.01574-14