Atomistry » Sodium » PDB 4qon-4r3n » 4qy9
Atomistry »
  Sodium »
    PDB 4qon-4r3n »
      4qy9 »

Sodium in PDB 4qy9: X-Ray Structure of the Adduct Between Hen Egg White Lysozyme and AUOXO3, A Cytotoxic Gold(III) Compound

Enzymatic activity of X-Ray Structure of the Adduct Between Hen Egg White Lysozyme and AUOXO3, A Cytotoxic Gold(III) Compound

All present enzymatic activity of X-Ray Structure of the Adduct Between Hen Egg White Lysozyme and AUOXO3, A Cytotoxic Gold(III) Compound:
3.2.1.17;

Protein crystallography data

The structure of X-Ray Structure of the Adduct Between Hen Egg White Lysozyme and AUOXO3, A Cytotoxic Gold(III) Compound, PDB code: 4qy9 was solved by I.Russo Krauss, A.Merlino, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 27.19 / 2.05
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 76.943, 76.943, 37.464, 90.00, 90.00, 90.00
R / Rfree (%) 18.5 / 28.9

Other elements in 4qy9:

The structure of X-Ray Structure of the Adduct Between Hen Egg White Lysozyme and AUOXO3, A Cytotoxic Gold(III) Compound also contains other interesting chemical elements:

Gold (Au) 2 atoms

Sodium Binding Sites:

The binding sites of Sodium atom in the X-Ray Structure of the Adduct Between Hen Egg White Lysozyme and AUOXO3, A Cytotoxic Gold(III) Compound (pdb code 4qy9). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the X-Ray Structure of the Adduct Between Hen Egg White Lysozyme and AUOXO3, A Cytotoxic Gold(III) Compound, PDB code: 4qy9:

Sodium binding site 1 out of 1 in 4qy9

Go back to Sodium Binding Sites List in 4qy9
Sodium binding site 1 out of 1 in the X-Ray Structure of the Adduct Between Hen Egg White Lysozyme and AUOXO3, A Cytotoxic Gold(III) Compound


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of X-Ray Structure of the Adduct Between Hen Egg White Lysozyme and AUOXO3, A Cytotoxic Gold(III) Compound within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na407

b:39.7
occ:1.00
 O A:SER60 2.1 35.0 1.0
O A:ARG73 2.3 41.7 1.0
O A:HOH536 2.4 43.4 1.0
OG A:SER72 2.5 47.8 1.0
O A:CYS64 2.6 29.6 1.0
O3 A:NO3403 2.6 52.8 1.0
C A:SER60 3.2 37.5 1.0
C A:ARG73 3.4 47.2 1.0
CB A:SER72 3.5 56.6 1.0
N A:NO3403 3.6 50.5 1.0
C A:CYS64 3.7 32.5 1.0
O2 A:NO3403 3.7 57.0 1.0
N A:ARG73 3.8 56.0 1.0
CA A:SER60 3.9 35.0 1.0
C A:SER72 4.0 58.0 1.0
CA A:ARG73 4.2 51.2 1.0
CA A:ASN65 4.2 35.0 1.0
CB A:SER60 4.2 32.9 1.0
N A:ASN74 4.3 44.4 1.0
N A:ARG61 4.3 38.9 1.0
C A:ARG61 4.3 43.7 1.0
N A:ASN65 4.3 34.1 1.0
CA A:SER72 4.4 57.1 1.0
O A:ARG61 4.5 48.1 1.0
N A:CYS64 4.5 31.8 1.0
CA A:ASN74 4.5 39.2 1.0
CB A:THR69 4.5 39.2 1.0
O A:SER72 4.6 57.4 1.0
N A:TRP62 4.6 41.7 1.0
CA A:ARG61 4.6 44.1 1.0
O1 A:NO3403 4.7 52.3 1.0
CB A:ASN74 4.7 37.7 1.0
CA A:CYS64 4.7 29.5 1.0
O A:THR69 4.8 39.1 1.0
ND2 A:ASN65 4.8 54.4 1.0
CG2 A:THR69 4.8 38.5 1.0
N A:TRP63 4.9 31.3 1.0
C A:TRP62 4.9 36.8 1.0
CB A:ASN65 5.0 35.0 1.0

Reference:

I.Russo Krauss, L.Messori, M.A.Cinellu, D.Marasco, R.Sirignano, A.Merlino. Interactions of Gold-Based Drugs with Proteins: the Structure and Stability of the Adduct Formed in the Reaction Between Lysozyme and the Cytotoxic Gold(III) Compound AUOXO3. Dalton Trans 2014.
ISSN: ESSN 1477-9234
PubMed: 25340580
DOI: 10.1039/C4DT02332C
Page generated: Mon Oct 7 18:07:12 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy