Sodium in PDB 4oq4: Crystal Structure of E18A Human Dj-1

The structure of Crystal Structure of E18A Human Dj-1, PDB code: 4oq4 was solved by J.Prahlad, D.N.Hauser, N.M.Milkovic, M.R.Cookson, M.A.Wilson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.39 / 1.49
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	74.682, 74.682, 74.848, 90.00, 90.00, 120.00
R / Rfree (%)	11.8 / 13.9

The binding sites of Sodium atom in the Crystal Structure of E18A Human Dj-1 (pdb code 4oq4). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of E18A Human Dj-1, PDB code: 4oq4:

Sodium binding site 1 out of 1 in the Crystal Structure of E18A Human Dj-1


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of E18A Human Dj-1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na201 b:26.4 occ:1.00 O A:HOH394 2.6 48.2 1.0 OE2 A:GLU163 2.7 28.2 1.0 O A:HOH465 2.9 33.4 1.0 N A:GLU163 3.0 13.2 1.0 O A:GLY159 3.1 17.9 1.0 N A:PHE162 3.1 12.7 1.0 O A:HOH445 3.2 48.3 1.0 C A:THR160 3.3 12.4 1.0 CB A:PHE162 3.4 12.6 1.0 CA A:THR160 3.4 12.6 1.0 CG A:GLU163 3.4 19.8 1.0 CD A:GLU163 3.5 25.4 1.0 CA A:PHE162 3.6 12.6 1.0 O A:THR160 3.6 12.8 1.0 N A:SER161 3.6 12.5 1.0 C A:PHE162 3.8 13.3 1.0 C A:GLY159 3.8 15.8 1.0 CB A:GLU163 3.8 16.3 1.0 N A:THR160 4.0 12.9 1.0 CA A:GLU163 4.0 13.7 1.0 C A:SER161 4.1 11.9 1.0 CD2 A:PHE162 4.2 16.9 1.0 CG A:PHE162 4.3 14.2 1.0 O A:HOH453 4.3 42.7 1.0 NH2 A:ARG145 4.4 25.1 1.0 CA A:SER161 4.5 12.0 1.0 CB A:THR160 4.7 12.9 1.0 OE1 A:GLU163 4.7 26.8 1.0 O A:HOH458 4.9 44.1 1.0 O A:PHE162 5.0 13.2 1.0

J.Prahlad, D.N.Hauser, N.M.Milkovic, M.R.Cookson, M.A.Wilson. Use of Cysteine-Reactive Cross-Linkers to Probe Conformational Flexibility of Human Dj-1 Demonstrates That GLU18 Mutations Are Dimers. J Neurochem V. 130 839 2014.
PubMed: 24832775
DOI: 10.1111/JNC.12763