Sodium in PDB 4op9: Urate Oxidase in Complex with 8-Azaxanthine

All present enzymatic activity of Urate Oxidase in Complex with 8-Azaxanthine:
1.7.3.3;

The structure of Urate Oxidase in Complex with 8-Azaxanthine, PDB code: 4op9 was solved by N.Colloc'h, T.Prange, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.58
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	80.109, 96.175, 105.407, 90.00, 90.00, 90.00
R / Rfree (%)	16.8 / 19.1

The binding sites of Sodium atom in the Urate Oxidase in Complex with 8-Azaxanthine (pdb code 4op9). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Urate Oxidase in Complex with 8-Azaxanthine, PDB code: 4op9:

Sodium binding site 1 out of 1 in the Urate Oxidase in Complex with 8-Azaxanthine


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Urate Oxidase in Complex with 8-Azaxanthine within 5.0Å range: probe atom residue distance (Å) B Occ A:Na402 b:27.5 occ:1.00 O A:HOH648 2.3 41.7 1.0 O A:ILE88 2.3 24.7 1.0 O A:ILE94 2.4 21.0 1.0 O A:TYR91 2.6 22.4 1.0 OE1 A:GLU136 2.7 35.7 1.0 O A:ASN92 3.3 30.4 1.0 C A:ILE88 3.3 23.3 1.0 C A:ILE94 3.6 20.0 1.0 CD A:GLU136 3.6 37.1 1.0 C A:TYR91 3.7 23.6 1.0 C A:ASN92 3.7 26.2 1.0 CA A:ILE88 3.7 21.7 1.0 CA A:ASN92 4.0 29.0 1.0 ND1 A:HIS95 4.1 26.0 1.0 OE2 A:GLU136 4.1 40.8 1.0 N A:ILE94 4.1 20.5 1.0 CB A:ILE88 4.2 22.8 1.0 N A:ASN92 4.3 25.5 1.0 CA A:ILE94 4.4 20.0 1.0 N A:HIS93 4.5 24.2 1.0 N A:HIS95 4.5 19.1 1.0 N A:GLU89 4.5 22.1 1.0 CE1 A:HIS95 4.5 27.3 1.0 CA A:HIS95 4.6 20.3 1.0 CG A:GLU136 4.7 34.4 1.0 O A:PHE87 4.8 20.4 1.0 CB A:ILE94 4.8 19.7 1.0 CA A:TYR91 4.9 22.8 1.0 N A:TYR91 4.9 23.2 1.0 C A:HIS93 4.9 21.6 1.0 CA A:GLU89 5.0 23.9 1.0

N.Colloc'h, T.Prange. Functinal Relevance of the Internal Cavity of Urate Oxidase Febs Lett. 2014.
ISSN: ISSN 0014-5793