Sodium in PDB 4o4w: Crystal Structure of Trichomonas Vaginalis Triosephosphate Isomerase ILE45-Gly Mutant (TVAG_497370)

All present enzymatic activity of Crystal Structure of Trichomonas Vaginalis Triosephosphate Isomerase ILE45-Gly Mutant (TVAG_497370):
5.3.1.1;

The structure of Crystal Structure of Trichomonas Vaginalis Triosephosphate Isomerase ILE45-Gly Mutant (TVAG_497370), PDB code: 4o4w was solved by S.Lara-Gonzalez, C.G.Benitez-Cardoza, L.G.Brieba, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	52.38 / 2.35
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	46.782, 56.010, 104.754, 90.00, 90.00, 90.00
R / Rfree (%)	19.4 / 23.2

The binding sites of Sodium atom in the Crystal Structure of Trichomonas Vaginalis Triosephosphate Isomerase ILE45-Gly Mutant (TVAG_497370) (pdb code 4o4w). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of Trichomonas Vaginalis Triosephosphate Isomerase ILE45-Gly Mutant (TVAG_497370), PDB code: 4o4w:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Crystal Structure of Trichomonas Vaginalis Triosephosphate Isomerase ILE45-Gly Mutant (TVAG_497370)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Trichomonas Vaginalis Triosephosphate Isomerase ILE45-Gly Mutant (TVAG_497370) within 5.0Å range: probe atom residue distance (Å) B Occ A:Na301 b:20.1 occ:1.00 O A:ALA222 2.3 18.2 1.0 O A:VAL227 2.4 20.2 1.0 OG A:SER251 2.4 21.2 1.0 O A:CYS224 2.4 22.8 1.0 CB A:SER251 3.2 19.7 1.0 C A:ALA222 3.5 17.9 1.0 C A:CYS224 3.6 19.0 1.0 C A:VAL227 3.6 20.1 1.0 CA A:SER251 3.9 23.6 1.0 C A:ALA223 4.0 20.8 1.0 N A:CYS224 4.1 22.1 1.0 O A:ALA223 4.2 21.3 1.0 CE1 A:PHE4 4.3 18.8 1.0 N A:VAL227 4.3 18.1 1.0 CA A:VAL227 4.3 17.7 1.0 CA A:ALA222 4.4 20.6 1.0 O A:PRO225 4.4 22.2 1.0 N A:ALA223 4.4 19.4 1.0 CB A:VAL227 4.4 20.4 1.0 C A:PRO225 4.4 18.3 1.0 CA A:CYS224 4.4 22.0 1.0 N A:PRO225 4.5 14.3 1.0 CA A:ALA223 4.5 21.2 1.0 CA A:PRO225 4.5 17.2 1.0 N A:ASP228 4.6 19.4 1.0 O A:SER251 4.6 32.6 1.0 C A:SER251 4.7 22.1 1.0 O A:LEU221 4.8 18.8 1.0 CA A:ASP228 4.8 18.2 1.0 CD1 A:PHE4 4.8 16.9 1.0 N A:ASP226 5.0 20.1 1.0

Sodium binding site 2 out of 2 in the Crystal Structure of Trichomonas Vaginalis Triosephosphate Isomerase ILE45-Gly Mutant (TVAG_497370)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of Trichomonas Vaginalis Triosephosphate Isomerase ILE45-Gly Mutant (TVAG_497370) within 5.0Å range: probe atom residue distance (Å) B Occ A:Na302 b:32.7 occ:1.00 O A:GLY156 2.2 32.2 1.0 OD1 A:ASP159 2.5 31.1 1.0 OD2 A:ASP159 2.6 39.3 1.0 CG A:ASP159 2.8 30.0 1.0 C A:GLY156 3.4 27.4 1.0 CB A:ASP159 4.2 25.1 1.0 N A:LYS157 4.3 26.8 1.0 CA A:GLY156 4.3 25.7 1.0 CA A:LYS157 4.3 29.1 1.0 OD2 A:ASP160 4.4 33.0 1.0 CD A:LYS157 4.5 28.0 1.0 CG A:ASP160 4.8 27.8 1.0 OD1 A:ASP160 4.9 24.1 1.0 C A:LYS157 5.0 26.1 1.0

S.Lara-Gonzalez, C.G.Benitez-Cardoza, L.G.Brieba. Engineering Mutants with Altered Dimer-Monomer Equilibrium Reveal the Existence of Stable Monomeric Triosephosphate Isomerases To Be Published.