Sodium »
PDB 4nxz-4obo »
4nxz »
Sodium in PDB 4nxz: Dna Polymerase Beta with O6MG in the Template Base Opposite to Incoming Non-Hydrolyzable Ttp with Manganese in the Active Site
Enzymatic activity of Dna Polymerase Beta with O6MG in the Template Base Opposite to Incoming Non-Hydrolyzable Ttp with Manganese in the Active Site
All present enzymatic activity of Dna Polymerase Beta with O6MG in the Template Base Opposite to Incoming Non-Hydrolyzable Ttp with Manganese in the Active Site:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of Dna Polymerase Beta with O6MG in the Template Base Opposite to Incoming Non-Hydrolyzable Ttp with Manganese in the Active Site, PDB code: 4nxz
was solved by
M.-C.Koag,
K.Min,
A.F.Monzingo,
S.Lee,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 19.97 / 2.56 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 50.803, 79.842, 55.442, 90.00, 107.05, 90.00 |
| R / Rfree (%) | 19 / 25.5 |
Other elements in 4nxz:
The structure of Dna Polymerase Beta with O6MG in the Template Base Opposite to Incoming Non-Hydrolyzable Ttp with Manganese in the Active Site also contains other interesting chemical elements:
| Manganese | (Mn) | 2 atoms |
Sodium Binding Sites:
The binding sites of Sodium atom in the Dna Polymerase Beta with O6MG in the Template Base Opposite to Incoming Non-Hydrolyzable Ttp with Manganese in the Active Site
(pdb code 4nxz). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Dna Polymerase Beta with O6MG in the Template Base Opposite to Incoming Non-Hydrolyzable Ttp with Manganese in the Active Site, PDB code: 4nxz:
Jump to Sodium binding site number: 1; 2;
In total 2 binding sites of Sodium where determined in the Dna Polymerase Beta with O6MG in the Template Base Opposite to Incoming Non-Hydrolyzable Ttp with Manganese in the Active Site, PDB code: 4nxz:
Jump to Sodium binding site number: 1; 2;
Sodium binding site 1 out of 2 in 4nxz
Go back to
Sodium Binding Sites List in 4nxz
Sodium binding site 1 out
of 2 in the Dna Polymerase Beta with O6MG in the Template Base Opposite to Incoming Non-Hydrolyzable Ttp with Manganese in the Active Site
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Sodium with other atoms in the Na binding
site number 1 of Dna Polymerase Beta with O6MG in the Template Base Opposite to Incoming Non-Hydrolyzable Ttp with Manganese in the Active Site within 5.0Å range:
|
Sodium binding site 2 out of 2 in 4nxz
Go back to
Sodium Binding Sites List in 4nxz
Sodium binding site 2 out
of 2 in the Dna Polymerase Beta with O6MG in the Template Base Opposite to Incoming Non-Hydrolyzable Ttp with Manganese in the Active Site
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Sodium with other atoms in the Na binding
site number 2 of Dna Polymerase Beta with O6MG in the Template Base Opposite to Incoming Non-Hydrolyzable Ttp with Manganese in the Active Site within 5.0Å range:
|
Reference:
M.C.Koag,
S.Lee.
Metal-Dependent Conformational Activation Explains Highly Promutagenic Replication Across O6-Methylguanine By Human Dna Polymerase Beta. J.Am.Chem.Soc. V. 136 5709 2014.
ISSN: ISSN 0002-7863
PubMed: 24694247
DOI: 10.1021/JA500172D
Page generated: Mon Oct 7 17:20:00 2024
ISSN: ISSN 0002-7863
PubMed: 24694247
DOI: 10.1021/JA500172D
Last articles
Zn in 9JYWZn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
