Sodium in PDB 4hc6: Mycobacterium Tuberculosis RV2523CE77A X-Ray Structure Solved with 1.8 Angstrom Resolution

All present enzymatic activity of Mycobacterium Tuberculosis RV2523CE77A X-Ray Structure Solved with 1.8 Angstrom Resolution:
2.7.8.7;

The structure of Mycobacterium Tuberculosis RV2523CE77A X-Ray Structure Solved with 1.8 Angstrom Resolution, PDB code: 4hc6 was solved by H.-B.Kim, G.-W.Han, L.-W.Hung, C.T.Terwilliger, C.-Y.Kim, Integratedcenter For Structure And Function Innovation (Isfi), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.58 / 1.80
Space group	P 21 3
Cell size a, b, c (Å), α, β, γ (°)	73.272, 73.272, 73.272, 90.00, 90.00, 90.00
R / Rfree (%)	17.6 / 21.2

The structure of Mycobacterium Tuberculosis RV2523CE77A X-Ray Structure Solved with 1.8 Angstrom Resolution also contains other interesting chemical elements:

Bromine	(Br)	3 atoms
Chlorine	(Cl)	7 atoms

The binding sites of Sodium atom in the Mycobacterium Tuberculosis RV2523CE77A X-Ray Structure Solved with 1.8 Angstrom Resolution (pdb code 4hc6). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Mycobacterium Tuberculosis RV2523CE77A X-Ray Structure Solved with 1.8 Angstrom Resolution, PDB code: 4hc6:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Mycobacterium Tuberculosis RV2523CE77A X-Ray Structure Solved with 1.8 Angstrom Resolution


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Mycobacterium Tuberculosis RV2523CE77A X-Ray Structure Solved with 1.8 Angstrom Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Na209 b:44.2 occ:1.00 O A:HOH350 2.0 8.1 1.0 O A:HOH328 2.2 33.0 1.0 NA A:NA210 2.6 29.3 1.0 ND1 A:HIS111 3.8 17.0 1.0 CB A:HIS111 3.8 14.6 1.0 CA A:HIS111 4.0 14.4 1.0 O A:HOH312 4.0 27.6 1.0 O A:VAL112 4.1 11.9 1.0 N A:VAL112 4.1 13.8 1.0 CG A:HIS111 4.3 13.4 1.0 C A:HIS111 4.4 14.5 1.0 O A:HOH352 4.5 35.3 1.0 C A:VAL112 4.9 13.2 1.0 CE1 A:HIS111 4.9 17.5 1.0

Sodium binding site 2 out of 2 in the Mycobacterium Tuberculosis RV2523CE77A X-Ray Structure Solved with 1.8 Angstrom Resolution


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Mycobacterium Tuberculosis RV2523CE77A X-Ray Structure Solved with 1.8 Angstrom Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Na210 b:29.3 occ:1.00 O A:VAL112 2.4 11.9 1.0 NA A:NA209 2.6 44.2 1.0 O A:HOH328 2.9 33.0 1.0 O A:HOH312 3.1 27.6 1.0 C A:VAL112 3.5 13.2 1.0 N A:VAL112 4.1 13.8 1.0 CB A:SER113 4.1 11.9 1.0 N A:SER113 4.3 12.1 1.0 CA A:SER113 4.3 11.9 1.0 CA A:VAL112 4.4 13.5 1.0 O A:HOH350 4.5 8.1 1.0 CL A:CL202 4.8 11.3 1.0 OG A:SER113 4.9 12.8 1.0 CG A:PRO93 4.9 16.0 1.0

H.-B.Kim, G.-W.Han, L.-W.Hung, C.T.Terwilliger, C.-Y.Kim. Mycobacterium Tuberculosis RV2523CE77A X-Ray Structure Solved with 1.8 Angstrom Resolution To Be Published.