Atomistry » Sodium » PDB 4gxj-4hfc » 4h5r
Atomistry »
  Sodium »
    PDB 4gxj-4hfc »
      4h5r »

Sodium in PDB 4h5r: HSC70 Nbd with Na, Cl and Glycerol

Protein crystallography data

The structure of HSC70 Nbd with Na, Cl and Glycerol, PDB code: 4h5r was solved by B.Stec, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 48.00 / 1.64
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 138.637, 102.462, 77.776, 90.00, 119.80, 90.00
R / Rfree (%) 20.5 / 23.9

Other elements in 4h5r:

The structure of HSC70 Nbd with Na, Cl and Glycerol also contains other interesting chemical elements:

Chlorine (Cl) 2 atoms

Sodium Binding Sites:

The binding sites of Sodium atom in the HSC70 Nbd with Na, Cl and Glycerol (pdb code 4h5r). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the HSC70 Nbd with Na, Cl and Glycerol, PDB code: 4h5r:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in 4h5r

Go back to Sodium Binding Sites List in 4h5r
Sodium binding site 1 out of 2 in the HSC70 Nbd with Na, Cl and Glycerol


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of HSC70 Nbd with Na, Cl and Glycerol within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na401

b:32.1
occ:1.00
O A:HOH501 1.9 18.0 1.0
O A:HOH502 1.9 19.2 1.0
O3 A:PO4402 2.1 20.0 1.0
O A:HOH503 2.3 20.1 1.0
O A:HOH505 2.4 34.0 1.0
O A:HOH504 2.5 20.9 1.0
P A:PO4402 3.3 20.4 1.0
O1 A:PO4402 3.4 18.1 1.0
O A:HOH608 3.6 27.3 1.0
OE1 A:GLU175 3.9 20.0 1.0
O A:HOH680 3.9 28.7 1.0
O A:HOH606 4.0 16.6 1.0
O2 A:PO4402 4.0 21.1 1.0
OD2 A:ASP199 4.1 20.7 1.0
OD1 A:ASP199 4.1 16.3 1.0
OD2 A:ASP10 4.3 16.4 1.0
OD1 A:ASP10 4.4 17.8 1.0
CG A:ASP199 4.5 18.0 1.0
O4 A:PO4402 4.5 20.6 1.0
CD A:GLU175 4.6 19.1 1.0
CL A:CL403 4.7 26.4 1.0
CG A:ASP10 4.8 18.4 1.0
CG1 A:VAL337 4.9 19.1 1.0

Sodium binding site 2 out of 2 in 4h5r

Go back to Sodium Binding Sites List in 4h5r
Sodium binding site 2 out of 2 in the HSC70 Nbd with Na, Cl and Glycerol


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of HSC70 Nbd with Na, Cl and Glycerol within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Na401

b:34.6
occ:1.00
O B:HOH501 1.8 18.1 1.0
O B:HOH502 2.1 20.4 1.0
O2 B:PO4402 2.2 19.8 1.0
O B:HOH503 2.4 21.0 1.0
O B:HOH504 2.5 21.6 1.0
P B:PO4402 3.4 20.1 1.0
O B:HOH505 3.4 35.2 1.0
O4 B:PO4402 3.4 17.9 1.0
O B:HOH646 3.7 32.9 1.0
O B:HOH723 3.8 29.9 1.0
OE1 B:GLU175 3.9 17.0 1.0
OD2 B:ASP199 3.9 19.6 1.0
OD1 B:ASP199 4.0 17.9 1.0
O1 B:PO4402 4.1 20.2 1.0
O B:HOH640 4.1 21.2 1.0
OD2 B:ASP10 4.3 16.1 1.0
OD1 B:ASP10 4.4 18.4 1.0
CG B:ASP199 4.4 18.1 1.0
O3 B:PO4402 4.5 22.2 1.0
CD B:GLU175 4.6 18.2 1.0
CG1 B:VAL337 4.8 17.6 1.0
CG B:ASP10 4.8 17.9 1.0
CL B:CL403 4.9 22.6 1.0

Reference:

Z.Ziming, J.Cellitti, P.Teriete, M.Pellecchia, B.Stec. New Crystal Structures of Hsc-70 Atp Binding Domain Confirm the Role of Individual Binding Pockets and Suggests A New Method of Inhibition. To Be Published.
Page generated: Mon Oct 7 15:44:36 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy