Sodium in PDB 4ch2: Low-Salt Crystal Structure of A Thrombin-Gpibalpha Peptide Complex

All present enzymatic activity of Low-Salt Crystal Structure of A Thrombin-Gpibalpha Peptide Complex:
3.4.21.5;

The structure of Low-Salt Crystal Structure of A Thrombin-Gpibalpha Peptide Complex, PDB code: 4ch2 was solved by B.C.Lechtenberg, S.M.V.Freund, J.A.Huntington, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.10 / 1.60
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	149.570, 50.560, 76.280, 90.00, 97.15, 90.00
R / Rfree (%)	15.452 / 18.73

The binding sites of Sodium atom in the Low-Salt Crystal Structure of A Thrombin-Gpibalpha Peptide Complex (pdb code 4ch2). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Low-Salt Crystal Structure of A Thrombin-Gpibalpha Peptide Complex, PDB code: 4ch2:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Low-Salt Crystal Structure of A Thrombin-Gpibalpha Peptide Complex


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Low-Salt Crystal Structure of A Thrombin-Gpibalpha Peptide Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Na3001 b:13.4 occ:1.00 O B:HOH2187 2.3 15.0 1.0 O B:ARG553 2.3 13.2 1.0 O B:LYS556 2.4 12.1 1.0 O B:HOH2170 2.4 11.5 1.0 O B:HOH2205 2.4 12.0 1.0 O B:HOH2172 2.7 13.7 1.0 C B:ARG553 3.4 13.8 1.0 C B:LYS556 3.5 11.5 1.0 N B:LYS556 3.8 12.7 1.0 O B:HOH2167 3.9 12.1 1.0 O B:HOH2185 4.0 17.3 1.0 N B:ARG553 4.0 12.8 1.0 O B:TYR510 4.0 11.7 1.0 CA B:LYS556 4.1 12.5 1.0 C B:ASP552 4.2 12.8 1.0 N B:GLY555 4.2 14.4 1.0 O B:HOH2171 4.2 10.2 1.0 N B:ASP554 4.3 14.6 1.0 CA B:ASP554 4.3 15.4 1.0 CA B:ARG553 4.3 13.6 1.0 CA B:ASP552 4.5 12.2 1.0 C B:ASP554 4.5 15.1 1.0 N B:TYR557 4.5 10.4 1.0 O B:HOH2186 4.6 11.6 1.0 O B:ASP552 4.6 13.8 1.0 CB B:LYS556 4.6 13.0 1.0 OD1 B:ASP552 4.7 12.5 1.0 CA B:TYR557 4.8 9.7 1.0 C B:GLY555 4.9 14.2 1.0

Sodium binding site 2 out of 2 in the Low-Salt Crystal Structure of A Thrombin-Gpibalpha Peptide Complex


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Low-Salt Crystal Structure of A Thrombin-Gpibalpha Peptide Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Na3001 b:15.0 occ:1.00 O D:HOH2150 2.3 17.9 1.0 O D:LYS556 2.3 15.6 1.0 O D:HOH2167 2.4 16.0 1.0 O D:ARG553 2.4 17.2 1.0 O D:HOH2142 2.4 11.0 1.0 O D:HOH2144 2.7 17.1 1.0 C D:ARG553 3.4 18.5 1.0 C D:LYS556 3.5 16.8 1.0 O D:HOH2139 3.9 14.8 1.0 O D:HOH2171 3.9 17.9 1.0 N D:LYS556 3.9 18.2 1.0 N D:ARG553 4.0 17.3 1.0 O D:TYR510 4.1 16.8 1.0 O D:HOH2143 4.1 12.5 1.0 C D:ASP552 4.1 16.8 1.0 N D:GLY555 4.2 20.3 1.0 N D:ASP554 4.2 19.7 1.0 CA D:LYS556 4.2 17.8 1.0 CA D:ASP554 4.2 20.6 1.0 CA D:ARG553 4.3 18.8 1.0 CA D:ASP552 4.4 15.2 1.0 N D:TYR557 4.5 15.2 1.0 C D:ASP554 4.5 21.0 1.0 O D:HOH2151 4.6 16.7 1.0 OD1 D:ASP552 4.6 17.3 1.0 O D:ASP552 4.6 17.9 1.0 CB D:LYS556 4.6 19.2 1.0 CA D:TYR557 4.8 14.4 1.0 C D:GLY555 4.9 19.0 1.0

B.C.Lechtenberg, S.M.V.Freund, J.A.Huntington. Gpibalpha Interacts Exclusively with Exosite II of Thrombin J.Mol.Biol. V. 426 881 2014.
ISSN: ISSN 0022-2836
PubMed: 24316004
DOI: 10.1016/J.JMB.2013.11.027