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Sodium in PDB 3v6o: Leptin Receptor-Antibody Complex

Protein crystallography data

The structure of Leptin Receptor-Antibody Complex, PDB code: 3v6o was solved by B.Carpenter, G.R.Hemsworth, R.J.Ross, P.J.Artymiuk, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 49.00 / 1.95
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 89.814, 118.829, 171.281, 90.00, 90.00, 90.00
R / Rfree (%) 17.1 / 21.3

Sodium Binding Sites:

The binding sites of Sodium atom in the Leptin Receptor-Antibody Complex (pdb code 3v6o). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Leptin Receptor-Antibody Complex, PDB code: 3v6o:

Sodium binding site 1 out of 1 in 3v6o

Go back to Sodium Binding Sites List in 3v6o
Sodium binding site 1 out of 1 in the Leptin Receptor-Antibody Complex


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Leptin Receptor-Antibody Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Na305

b:32.9
occ:1.00
O C:HOH555 2.3 32.1 1.0
O C:SER191 2.3 41.3 1.0
O C:TRP194 2.4 30.8 1.0
O C:HOH554 2.5 44.3 1.0
C C:TRP194 3.4 34.4 1.0
C C:SER191 3.5 41.5 1.0
CD C:PRO195 3.8 35.9 1.0
N C:PRO195 4.0 30.9 1.0
CA C:SER191 4.2 35.5 1.0
N C:TRP194 4.3 39.9 1.0
CB C:ALA135 4.4 37.5 1.0
CB C:SER191 4.4 36.3 1.0
CA C:TRP194 4.5 28.0 1.0
N C:SER192 4.5 36.5 1.0
O C:ALA135 4.7 42.3 1.0
CA C:SER192 4.7 37.3 1.0
C C:SER192 4.8 40.1 1.0

Reference:

B.Carpenter, G.R.Hemsworth, Z.Wu, M.Maamra, C.J.Strasburger, R.J.Ross, P.J.Artymiuk. Structure of the Human Obesity Receptor Leptin-Binding Domain Reveals the Mechanism of Leptin Antagonism By A Monoclonal Antibody. Structure V. 20 487 2012.
ISSN: ISSN 0969-2126
PubMed: 22405007
DOI: 10.1016/J.STR.2012.01.019
Page generated: Tue Dec 15 06:28:17 2020

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