Sodium in PDB 3v31: Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2

All present enzymatic activity of Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2:
3.5.1.98;

The structure of Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2, PDB code: 3v31 was solved by R.Lam, C.Xu, C.B.Bian, J.Kania, C.Bountra, J.Weigelt, C.H.Arrowsmith, A.M.Edwards, A.Bochkarev, J.Min, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.41 / 1.57
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	29.663, 52.822, 51.556, 90.00, 98.01, 90.00
R / Rfree (%)	17.4 / 20.5

The structure of Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2 also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Sodium atom in the Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2 (pdb code 3v31). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2, PDB code: 3v31:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na402 b:17.8 occ:1.00 O A:CYS237 2.3 21.1 1.0 O A:HOH556 2.3 17.8 1.0 O A:HOH570 2.3 26.9 1.0 O A:HOH594 2.7 22.3 1.0 C A:CYS237 3.4 19.1 1.0 O A:HOH575 4.1 24.1 1.0 CA A:CYS237 4.2 18.0 1.0 N A:GLY238 4.4 19.2 1.0 CB A:CYS237 4.6 17.5 1.0 CA A:GLY238 4.7 19.1 1.0

Sodium binding site 2 out of 2 in the Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na403 b:17.2 occ:1.00 O A:LEU308 2.4 16.3 1.0 O A:ILE311 2.4 19.5 1.0 O A:LEU305 2.5 20.5 1.0 O A:HOH629 3.5 22.6 1.0 C A:LEU308 3.6 16.1 1.0 C A:ILE311 3.6 20.4 1.0 C A:LEU305 3.8 19.2 1.0 O A:LYS306 3.9 21.6 1.0 CA A:LYS312 4.2 25.1 1.0 C A:LYS306 4.2 20.6 1.0 CA A:LYS306 4.3 20.5 1.0 N A:LYS312 4.4 22.9 1.0 CD A:LYS312 4.4 30.7 1.0 CG2 A:ILE311 4.4 17.2 1.0 N A:GLN309 4.5 15.9 1.0 CA A:LEU308 4.5 16.0 1.0 N A:LYS306 4.5 19.9 1.0 NE2 A:GLN309 4.5 20.9 1.0 CA A:GLN309 4.5 16.4 1.0 N A:LEU308 4.5 15.9 1.0 N A:ILE311 4.6 17.1 1.0 CA A:ILE311 4.7 18.7 1.0 CB A:LEU308 4.8 15.4 1.0 CA A:LEU305 4.9 18.7 1.0 C A:LYS312 5.0 26.3 1.0

C.Xu, J.Jin, C.Bian, R.Lam, R.Tian, R.Weist, L.You, J.Nie, A.Bochkarev, W.Tempel, C.S.Tan, G.A.Wasney, M.Vedadi, G.D.Gish, C.H.Arrowsmith, T.Pawson, X.J.Yang, J.Min. Sequence-Specific Recognition of A Pxlpxi/L Motif By An Ankyrin Repeat Tumbler Lock. Sci.Signal. V. 5 RA39 2012.
ISSN: ESSN 1937-9145
PubMed: 22649097
DOI: 10.1126/SCISIGNAL.2002979