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Atomistry » Sodium » PDB 3uq0-3v3r » 3uwp » |
Sodium in PDB 3uwp: Crystal Structure of DOT1L in Complex with 5-IodotubercidinEnzymatic activity of Crystal Structure of DOT1L in Complex with 5-Iodotubercidin
All present enzymatic activity of Crystal Structure of DOT1L in Complex with 5-Iodotubercidin:
2.1.1.43; Protein crystallography data
The structure of Crystal Structure of DOT1L in Complex with 5-Iodotubercidin, PDB code: 3uwp
was solved by
W.Yu,
W.Tempel,
D.Smil,
M.Schapira,
Y.Li,
M.Vedadi,
K.T.Nguyen,
A.K.Wernimont,
C.H.Arrowsmith,
A.M.Edwards,
C.Bountra,
J.Weigelt,
P.J.Brown,
Structural Genomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3uwp:
The structure of Crystal Structure of DOT1L in Complex with 5-Iodotubercidin also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Crystal Structure of DOT1L in Complex with 5-Iodotubercidin
(pdb code 3uwp). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of DOT1L in Complex with 5-Iodotubercidin, PDB code: 3uwp: Sodium binding site 1 out of 1 in 3uwpGo back to Sodium Binding Sites List in 3uwp
Sodium binding site 1 out
of 1 in the Crystal Structure of DOT1L in Complex with 5-Iodotubercidin
Mono view Stereo pair view
Reference:
W.Yu,
E.J.Chory,
A.K.Wernimont,
W.Tempel,
A.Scopton,
A.Federation,
J.J.Marineau,
J.Qi,
D.Barsyte-Lovejoy,
J.Yi,
R.Marcellus,
R.E.Iacob,
J.R.Engen,
C.Griffin,
A.Aman,
E.Wienholds,
F.Li,
J.Pineda,
G.Estiu,
T.Shatseva,
T.Hajian,
R.Al-Awar,
J.E.Dick,
M.Vedadi,
P.J.Brown,
C.H.Arrowsmith,
J.E.Bradner,
M.Schapira.
Catalytic Site Remodelling of the DOT1L Methyltransferase By Selective Inhibitors. Nat Commun V. 3 1288 2012.
Page generated: Tue Dec 15 06:27:59 2020
ISSN: ESSN 2041-1723 PubMed: 23250418 DOI: 10.1038/NCOMMS2304 |
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