Sodium in PDB 3uub: The Glic Pentameric Ligand-Gated Ion Channel LOOP2-21' Mutant Reduced in Solution

The structure of The Glic Pentameric Ligand-Gated Ion Channel LOOP2-21' Mutant Reduced in Solution, PDB code: 3uub was solved by L.Sauguet, H.Nury, P.J.Corringer, M.Delarue, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.36 / 2.90
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	182.130, 133.490, 319.690, 90.00, 102.64, 90.00
R / Rfree (%)	21.8 / 22.1

The structure of The Glic Pentameric Ligand-Gated Ion Channel LOOP2-21' Mutant Reduced in Solution also contains other interesting chemical elements:

Chlorine

(Cl)

10 atoms

The binding sites of Sodium atom in the The Glic Pentameric Ligand-Gated Ion Channel LOOP2-21' Mutant Reduced in Solution (pdb code 3uub). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the The Glic Pentameric Ligand-Gated Ion Channel LOOP2-21' Mutant Reduced in Solution, PDB code: 3uub:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the The Glic Pentameric Ligand-Gated Ion Channel LOOP2-21' Mutant Reduced in Solution


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of The Glic Pentameric Ligand-Gated Ion Channel LOOP2-21' Mutant Reduced in Solution within 5.0Å range: probe atom residue distance (Å) B Occ A:Na323 b:87.0 occ:1.00 OG1 A:THR226 3.9 56.4 1.0 OG1 E:THR226 4.0 55.4 1.0 OG1 B:THR226 4.1 56.1 1.0 OG1 D:THR226 4.2 53.6 1.0 OG1 C:THR226 4.3 64.7 1.0 CG2 E:THR226 4.9 49.9 1.0 CG2 A:THR226 5.0 47.3 1.0

Sodium binding site 2 out of 2 in the The Glic Pentameric Ligand-Gated Ion Channel LOOP2-21' Mutant Reduced in Solution


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of The Glic Pentameric Ligand-Gated Ion Channel LOOP2-21' Mutant Reduced in Solution within 5.0Å range: probe atom residue distance (Å) B Occ F:Na322 b:83.4 occ:1.00 OG1 J:THR226 4.0 59.2 1.0 OG1 F:THR226 4.0 59.9 1.0 OG1 I:THR226 4.1 59.8 1.0 OG1 H:THR226 4.2 52.2 1.0 OG1 G:THR226 4.2 52.3 1.0

M.S.Prevost, L.Sauguet, H.Nury, C.Van Renterghem, C.Huon, F.Poitevin, M.Baaden, M.Delarue, P.J.Corringer. A Locally Closed Conformation of A Bacterial Pentameric Proton-Gated Ion Channel. Nat.Struct.Mol.Biol. V. 19 642 2012.
ISSN: ISSN 1545-9993
PubMed: 22580559
DOI: 10.1038/NSMB.2307