Sodium in PDB 3uu5: The Glic Pentameric Ligand-Gated Ion Channel LOOP2-20' Mutant Reduced in Solution

The structure of The Glic Pentameric Ligand-Gated Ion Channel LOOP2-20' Mutant Reduced in Solution, PDB code: 3uu5 was solved by L.Sauguet, H.Nury, P.J.Corringer, M.Delarue, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.40 / 2.90
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	181.860, 132.980, 160.420, 90.00, 102.42, 90.00
R / Rfree (%)	20.4 / 21.8

The structure of The Glic Pentameric Ligand-Gated Ion Channel LOOP2-20' Mutant Reduced in Solution also contains other interesting chemical elements:

Chlorine

(Cl)

5 atoms

The binding sites of Sodium atom in the The Glic Pentameric Ligand-Gated Ion Channel LOOP2-20' Mutant Reduced in Solution (pdb code 3uu5). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the The Glic Pentameric Ligand-Gated Ion Channel LOOP2-20' Mutant Reduced in Solution, PDB code: 3uu5:

Sodium binding site 1 out of 1 in the The Glic Pentameric Ligand-Gated Ion Channel LOOP2-20' Mutant Reduced in Solution


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of The Glic Pentameric Ligand-Gated Ion Channel LOOP2-20' Mutant Reduced in Solution within 5.0Å range: probe atom residue distance (Å) B Occ A:Na324 b:99.2 occ:1.00 OE2 A:GLU222 3.3 0.8 0.5 OG1 C:THR226 4.0 77.8 1.0 OE1 C:GLU222 4.0 0.0 0.5 OG1 D:THR226 4.1 77.4 1.0 CD A:GLU222 4.4 1.0 0.5 OG1 B:THR226 4.4 80.8 1.0 OG1 E:THR226 4.4 77.7 1.0 OG1 A:THR226 4.6 75.3 1.0 CD C:GLU222 4.9 1.0 0.5 OE1 A:GLU222 4.9 97.9 0.5

M.S.Prevost, L.Sauguet, H.Nury, C.Van Renterghem, C.Huon, F.Poitevin, M.Baaden, M.Delarue, P.J.Corringer. A Locally Closed Conformation of A Bacterial Pentameric Proton-Gated Ion Channel. Nat.Struct.Mol.Biol. V. 19 642 2012.
ISSN: ISSN 1545-9993
PubMed: 22580559
DOI: 10.1038/NSMB.2307