Sodium in PDB 3uq4: X-Ray Structure of A Pentameric Ligand Gated Ion Channel From Erwinia Chrysanthemi (Elic) Mutant F247L (F16L)

The structure of X-Ray Structure of A Pentameric Ligand Gated Ion Channel From Erwinia Chrysanthemi (Elic) Mutant F247L (F16L), PDB code: 3uq4 was solved by G.Gonzalez-Gutierrez, T.Lukk, V.Agarwal, D.Papke, S.K.Nair, C.Grosman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.93 / 3.50
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	105.350, 266.940, 110.840, 90.00, 109.60, 90.00
R / Rfree (%)	21.5 / 23.9

The binding sites of Sodium atom in the X-Ray Structure of A Pentameric Ligand Gated Ion Channel From Erwinia Chrysanthemi (Elic) Mutant F247L (F16L) (pdb code 3uq4). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the X-Ray Structure of A Pentameric Ligand Gated Ion Channel From Erwinia Chrysanthemi (Elic) Mutant F247L (F16L), PDB code: 3uq4:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the X-Ray Structure of A Pentameric Ligand Gated Ion Channel From Erwinia Chrysanthemi (Elic) Mutant F247L (F16L)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of X-Ray Structure of A Pentameric Ligand Gated Ion Channel From Erwinia Chrysanthemi (Elic) Mutant F247L (F16L) within 5.0Å range: probe atom residue distance (Å) B Occ A:Na323 b:48.9 occ:1.00 OD1 C:ASN251 2.8 0.8 1.0 OD1 D:ASN251 3.0 0.6 1.0 OD1 B:ASN251 3.0 0.3 1.0 OD1 E:ASN251 3.2 0.8 1.0 OD1 A:ASN251 3.3 0.5 1.0 CG C:ASN251 3.8 98.4 1.0 CG B:ASN251 3.9 89.4 1.0 CG D:ASN251 4.0 96.3 1.0 CG A:ASN251 4.2 89.9 1.0 CG E:ASN251 4.2 92.9 1.0 ND2 C:ASN251 4.4 97.3 1.0 ND2 B:ASN251 4.4 89.8 1.0 ND2 D:ASN251 4.6 94.4 1.0 ND2 A:ASN251 4.7 85.1 1.0 ND2 E:ASN251 4.8 91.4 1.0 CB C:ASN251 5.0 71.4 1.0

Sodium binding site 2 out of 2 in the X-Ray Structure of A Pentameric Ligand Gated Ion Channel From Erwinia Chrysanthemi (Elic) Mutant F247L (F16L)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of X-Ray Structure of A Pentameric Ligand Gated Ion Channel From Erwinia Chrysanthemi (Elic) Mutant F247L (F16L) within 5.0Å range: probe atom residue distance (Å) B Occ F:Na323 b:50.0 occ:1.00 OD1 I:ASN251 2.6 0.0 1.0 OD1 H:ASN251 2.8 0.4 1.0 OD1 J:ASN251 2.9 0.2 1.0 OD1 F:ASN251 2.9 0.5 1.0 OD1 G:ASN251 3.0 0.8 1.0 CG I:ASN251 3.7 97.1 1.0 CG H:ASN251 3.8 92.5 1.0 CG J:ASN251 4.0 87.6 1.0 CG F:ASN251 4.0 84.4 1.0 CG G:ASN251 4.0 91.0 1.0 ND2 I:ASN251 4.2 90.4 1.0 ND2 H:ASN251 4.2 87.9 1.0 ND2 F:ASN251 4.5 81.8 1.0 ND2 G:ASN251 4.5 83.1 1.0 ND2 J:ASN251 4.5 87.1 1.0 CB I:ASN251 4.9 73.8 1.0

G.Gonzalez-Gutierrez, T.Lukk, V.Agarwal, D.Papke, S.K.Nair, C.Grosman. Mutations That Stabilize the Open State of the Erwinia Chrisanthemi Ligand-Gated Ion Channel Fail to Change the Conformation of the Pore Domain in Crystals. Proc.Natl.Acad.Sci.Usa V. 109 6331 2012.
ISSN: ISSN 0027-8424
PubMed: 22474383
DOI: 10.1073/PNAS.1119268109