Atomistry » Sodium » PDB 3tkj-3tzl » 3tkw
Atomistry »
  Sodium »
    PDB 3tkj-3tzl »
      3tkw »

Sodium in PDB 3tkw: Crystal Structure of Hiv Protease Model Precursor/Darunavir Complex

Enzymatic activity of Crystal Structure of Hiv Protease Model Precursor/Darunavir Complex

All present enzymatic activity of Crystal Structure of Hiv Protease Model Precursor/Darunavir Complex:
3.4.23.16;

Protein crystallography data

The structure of Crystal Structure of Hiv Protease Model Precursor/Darunavir Complex, PDB code: 3tkw was solved by J.Agniswamy, J.Sayer, I.Weber, J.Louis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 10.00 / 1.55
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 59.317, 86.223, 45.951, 90.00, 90.00, 90.00
R / Rfree (%) 16.7 / 23.1

Other elements in 3tkw:

The structure of Crystal Structure of Hiv Protease Model Precursor/Darunavir Complex also contains other interesting chemical elements:

Chlorine (Cl) 3 atoms

Sodium Binding Sites:

The binding sites of Sodium atom in the Crystal Structure of Hiv Protease Model Precursor/Darunavir Complex (pdb code 3tkw). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Hiv Protease Model Precursor/Darunavir Complex, PDB code: 3tkw:

Sodium binding site 1 out of 1 in 3tkw

Go back to Sodium Binding Sites List in 3tkw
Sodium binding site 1 out of 1 in the Crystal Structure of Hiv Protease Model Precursor/Darunavir Complex


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Hiv Protease Model Precursor/Darunavir Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na611

b:36.6
occ:1.00
 O A:HOH1054 2.3 30.6 1.0
O A:HOH1078 2.3 41.6 1.0
O A:ASP60 2.4 26.4 1.0
O A:HOH1062 2.5 36.9 1.0
O A:HOH1080 2.6 41.6 1.0
O A:HOH1027 2.6 29.8 1.0
C A:ASP60 3.4 24.0 1.0
N A:ASP60 3.8 22.8 1.0
O A:HOH1077 3.9 45.9 1.0
CA A:ASP60 4.1 22.4 1.0
O A:ARG41 4.1 26.8 1.0
N A:ARG41 4.5 31.4 1.0
N A:GLN61 4.5 25.2 1.0
CB A:ASP60 4.5 26.7 1.0
CD1 A:ILE62 4.5 23.3 1.0
O A:GLN61 4.5 28.2 1.0
CB A:GLN61 4.6 28.2 1.0
O A:PRO39 4.6 33.3 1.0
C A:GLN61 4.7 24.5 1.0
C A:TYR59 4.7 21.0 1.0
CA A:GLN61 4.8 23.8 1.0
CA A:GLY40 4.9 33.0 1.0

Reference:

J.Agniswamy, J.M.Sayer, I.T.Weber, J.M.Louis. Terminal Interface Conformations Modulate Dimer Stability Prior to Amino Terminal Autoprocessing of Hiv-1 Protease. Biochemistry V. 51 1041 2012.
ISSN: ISSN 0006-2960
PubMed: 22242794
DOI: 10.1021/BI201809S
Page generated: Mon Oct 7 13:18:41 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy