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Atomistry » Sodium » PDB 3qq0-3r57 » 3qri » |
Sodium in PDB 3qri: The Crystal Structure of Human ABL1 Kinase Domain in Complex with Dcc- 2036Enzymatic activity of The Crystal Structure of Human ABL1 Kinase Domain in Complex with Dcc- 2036
All present enzymatic activity of The Crystal Structure of Human ABL1 Kinase Domain in Complex with Dcc- 2036:
2.7.10.2; Protein crystallography data
The structure of The Crystal Structure of Human ABL1 Kinase Domain in Complex with Dcc- 2036, PDB code: 3qri
was solved by
W.W.Chan,
S.C.Wise,
M.D.Kaufman,
Y.M.Ahn,
C.L.Ensinger,
T.Haack,
M.M.Hood,
J.Jones,
J.W.Lord,
W.P.Lu,
D.Miller,
W.C.Patt,
B.D.Smith,
P.A.Petillo,
T.J.Rutkoski,
H.Telikepalli,
L.Vogeti,
T.Yao,
L.Chun,
R.Clark,
P.Evangelista,
L.C.Gavrilescu,
K.Lazarides,
V.M.Zaleskas,
L.J.Stewart,
R.A.Van Etten,
D.L.Flynn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3qri:
The structure of The Crystal Structure of Human ABL1 Kinase Domain in Complex with Dcc- 2036 also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the The Crystal Structure of Human ABL1 Kinase Domain in Complex with Dcc- 2036
(pdb code 3qri). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the The Crystal Structure of Human ABL1 Kinase Domain in Complex with Dcc- 2036, PDB code: 3qri: Jump to Sodium binding site number: 1; 2; Sodium binding site 1 out of 2 in 3qriGo back to Sodium Binding Sites List in 3qri
Sodium binding site 1 out
of 2 in the The Crystal Structure of Human ABL1 Kinase Domain in Complex with Dcc- 2036
Mono view Stereo pair view
Sodium binding site 2 out of 2 in 3qriGo back to Sodium Binding Sites List in 3qri
Sodium binding site 2 out
of 2 in the The Crystal Structure of Human ABL1 Kinase Domain in Complex with Dcc- 2036
Mono view Stereo pair view
Reference:
W.W.Chan,
S.C.Wise,
M.D.Kaufman,
Y.M.Ahn,
C.L.Ensinger,
T.Haack,
M.M.Hood,
J.Jones,
J.W.Lord,
W.P.Lu,
D.Miller,
W.C.Patt,
B.D.Smith,
P.A.Petillo,
T.J.Rutkoski,
H.Telikepalli,
L.Vogeti,
T.Yao,
L.Chun,
R.Clark,
P.Evangelista,
L.C.Gavrilescu,
K.Lazarides,
V.M.Zaleskas,
L.J.Stewart,
R.A.Van Etten,
D.L.Flynn.
Conformational Control Inhibition of the Bcr-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, By the Switch-Control Inhibitor Dcc-2036. Cancer Cell V. 19 556 2011.
Page generated: Tue Dec 15 06:23:02 2020
ISSN: ISSN 1535-6108 PubMed: 21481795 DOI: 10.1016/J.CCR.2011.03.003 |
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