Sodium in PDB 3ntt: Structural Insights of Adeno-Associated Virus 5. A Gene Therapy Vector For Cystic Fibrosis

The structure of Structural Insights of Adeno-Associated Virus 5. A Gene Therapy Vector For Cystic Fibrosis, PDB code: 3ntt was solved by L.Govindasamy, M.Dimattia, J.A.Chiorini, R.Mckenna, N.Muzyczka, M.Agbandje-Mckenna, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.96 / 3.45
Space group	P 21 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	264.700, 447.900, 629.700, 90.00, 90.00, 90.00
R / Rfree (%)	25.2 / 25.2

The binding sites of Sodium atom in the Structural Insights of Adeno-Associated Virus 5. A Gene Therapy Vector For Cystic Fibrosis (pdb code 3ntt). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Structural Insights of Adeno-Associated Virus 5. A Gene Therapy Vector For Cystic Fibrosis, PDB code: 3ntt:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in the Structural Insights of Adeno-Associated Virus 5. A Gene Therapy Vector For Cystic Fibrosis


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structural Insights of Adeno-Associated Virus 5. A Gene Therapy Vector For Cystic Fibrosis within 5.0Å range: probe atom residue distance (Å) B Occ A:Na726 b:20.6 occ:1.00 OD1 A:ASN243 3.5 76.9 1.0 NH1 A:ARG248 4.1 75.7 1.0 NE2 A:GLN365 4.2 64.0 1.0 N A:ASN243 4.3 51.1 1.0 CD2 A:TYR242 4.4 29.3 1.0 CG A:ASN243 4.7 72.7 1.0 OE1 A:GLN365 4.8 73.0 1.0 CZ A:ARG248 4.8 89.3 1.0 CA A:ASN243 4.9 17.9 1.0 CD A:GLN365 4.9 38.9 1.0 NH2 A:ARG248 5.0 62.9 1.0 CB A:TYR242 5.0 37.0 1.0

Sodium binding site 2 out of 3 in the Structural Insights of Adeno-Associated Virus 5. A Gene Therapy Vector For Cystic Fibrosis


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Structural Insights of Adeno-Associated Virus 5. A Gene Therapy Vector For Cystic Fibrosis within 5.0Å range: probe atom residue distance (Å) B Occ A:Na727 b:8.9 occ:1.00 O A:ASN407 3.6 87.4 1.0 OH A:TYR406 4.4 38.2 1.0 CB A:HIS631 4.4 63.9 1.0 CZ A:TYR406 4.6 20.4 1.0 ND1 A:HIS631 4.7 99.3 1.0 O A:HIS631 4.7 83.5 1.0 CE1 A:TYR406 4.8 84.6 1.0 C A:ASN407 4.9 54.4 1.0

Sodium binding site 3 out of 3 in the Structural Insights of Adeno-Associated Virus 5. A Gene Therapy Vector For Cystic Fibrosis


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Structural Insights of Adeno-Associated Virus 5. A Gene Therapy Vector For Cystic Fibrosis within 5.0Å range: probe atom residue distance (Å) B Occ A:Na728 b:7.8 occ:1.00 O A:THR541 3.8 53.7 1.0 OD1 A:ASN546 4.1 79.3 1.0 CD2 A:TYR542 4.6 39.5 1.0 CE2 A:TYR542 4.6 73.4 1.0 CB A:ALA540 5.0 67.2 1.0 C A:THR541 5.0 62.5 1.0

L.Govindasamy, M.A.Dimattia, B.L.Gurda, S.Halder, R.Mckenna, J.A.Chiorini, N.Muzyczka, S.Zolotukhin, M.Agbandje-Mckenna. Structural Insights Into Adeno-Associated Virus Serotype 5. J.Virol. V. 87 11187 2013.
ISSN: ISSN 0022-538X
PubMed: 23926356
DOI: 10.1128/JVI.00867-13