Sodium in PDB 3iv2: Crystal Structure of Mature Apo-Cathepsin L C25A Mutant

All present enzymatic activity of Crystal Structure of Mature Apo-Cathepsin L C25A Mutant:
3.4.22.15;

The structure of Crystal Structure of Mature Apo-Cathepsin L C25A Mutant, PDB code: 3iv2 was solved by M.A.Adams-Cioaba, J.C.Krupa, J.S.Mort, C.Bountra, J.Weigelt, C.H.Arrowsmith, A.M.Edwards, A.Bochkarev, J.Min, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.00 / 2.20
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	61.959, 61.959, 206.288, 90.00, 90.00, 120.00
R / Rfree (%)	20.2 / 24.4

The binding sites of Sodium atom in the Crystal Structure of Mature Apo-Cathepsin L C25A Mutant (pdb code 3iv2). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Mature Apo-Cathepsin L C25A Mutant, PDB code: 3iv2:

Sodium binding site 1 out of 1 in the Crystal Structure of Mature Apo-Cathepsin L C25A Mutant


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Mature Apo-Cathepsin L C25A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ B:Na300 b:41.3 occ:1.00 O B:ASP55 2.6 13.8 1.0 N B:GLY58 2.9 15.7 1.0 C B:ASP55 3.1 14.7 1.0 C B:CYS56 3.3 14.9 1.0 CA B:GLY58 3.4 12.5 1.0 N B:CYS56 3.4 13.0 1.0 N B:SER57 3.4 15.3 1.0 CA B:CYS56 3.5 14.0 1.0 O B:CYS56 3.9 12.4 1.0 C B:SER57 4.0 16.5 1.0 CD B:PRO59 4.1 12.4 1.0 O B:VAL54 4.2 16.6 1.0 O B:HOH422 4.2 17.2 1.0 OE2 B:GLU95 4.3 44.6 1.0 CA B:SER57 4.3 15.4 1.0 CA B:ASP55 4.4 13.8 1.0 C B:GLY58 4.6 15.0 1.0 N B:PRO59 4.8 14.2 1.0 C B:VAL54 4.9 15.6 1.0

M.A.Adams-Cioaba, J.C.Krupa, C.Xu, J.S.Mort, J.Min. Structural Basis For the Recognition and Cleavage of Histone H3 By Cathepsin L. Nat Commun V. 2 197 2011.
ISSN: ESSN 2041-1723
PubMed: 21326229
DOI: 10.1038/NCOMMS1204