Sodium in PDB 3isq: Crystal Structure of Human 4-Hydroxyphenylpyruvate Dioxygenase

All present enzymatic activity of Crystal Structure of Human 4-Hydroxyphenylpyruvate Dioxygenase:
1.13.11.27;

The structure of Crystal Structure of Human 4-Hydroxyphenylpyruvate Dioxygenase, PDB code: 3isq was solved by E.S.Pilka, N.Shafqat, R.Cocking, J.E.Bray, T.Krojer, A.C.W.Pike, F.Vondelft, W.W.Yue, C.H.Arrowsmith, J.Weigelt, A.Edwards, C.Bountra, U.Oppermann, K.L.Kavanagh, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.60 / 1.75
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	99.206, 99.206, 87.726, 90.00, 90.00, 120.00
R / Rfree (%)	14.4 / 17.4

The structure of Crystal Structure of Human 4-Hydroxyphenylpyruvate Dioxygenase also contains other interesting chemical elements:

Cobalt	(Co)	1 atom
Chlorine	(Cl)	1 atom

The binding sites of Sodium atom in the Crystal Structure of Human 4-Hydroxyphenylpyruvate Dioxygenase (pdb code 3isq). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Human 4-Hydroxyphenylpyruvate Dioxygenase, PDB code: 3isq:

Sodium binding site 1 out of 1 in the Crystal Structure of Human 4-Hydroxyphenylpyruvate Dioxygenase


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Human 4-Hydroxyphenylpyruvate Dioxygenase within 5.0Å range: probe atom residue distance (Å) B Occ A:Na902 b:15.9 occ:1.00 O A:HOH445 1.6 17.6 1.0 O A:HOH479 1.9 11.1 0.5 O A:HOH436 2.1 27.6 1.0 NE2 A:HIS18 2.3 22.7 1.0 CE1 A:HIS18 3.2 22.4 1.0 CD2 A:HIS18 3.3 21.8 1.0 O A:HOH479 3.5 19.0 0.5 O A:HOH437 3.7 25.0 1.0 ND1 A:HIS18 4.4 20.6 1.0 CG A:HIS18 4.5 18.2 1.0

E.S.Pilka, N.Shafqat, R.Cocking, J.E.Bray, T.Krojer, A.C.W.Pike, F.Von Delft, W.W.Yue, C.H.Arrowsmith, J.Weigelt, A.Edwards, C.Bountra, U.Oppermann, K.L.Kavanagh. Crystal Structure of Human 4-Hydroxyphenylpyruvate Dioxygenase To Be Published.