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Sodium in PDB 3eqc: X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Ternary Complex with Compound 1, Atp-Gs and MG2P
Enzymatic activity of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Ternary Complex with Compound 1, Atp-Gs and MG2P
All present enzymatic activity of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Ternary Complex with Compound 1, Atp-Gs and MG2P:
2.7.12.2;
2.7.12.2;
Protein crystallography data
The structure of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Ternary Complex with Compound 1, Atp-Gs and MG2P, PDB code: 3eqc
was solved by
T.O.Fischmann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 50.00 / 1.80 |
| Space group | P 61 2 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 77.220, 77.220, 222.050, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 19.9 / 23.5 |
Other elements in 3eqc:
The structure of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Ternary Complex with Compound 1, Atp-Gs and MG2P also contains other interesting chemical elements:
| Fluorine | (F) | 2 atoms |
| Magnesium | (Mg) | 1 atom |
| Iodine | (I) | 1 atom |
| Calcium | (Ca) | 1 atom |
| Chlorine | (Cl) | 1 atom |
Sodium Binding Sites:
The binding sites of Sodium atom in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Ternary Complex with Compound 1, Atp-Gs and MG2P
(pdb code 3eqc). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Ternary Complex with Compound 1, Atp-Gs and MG2P, PDB code: 3eqc:
In total only one binding site of Sodium was determined in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Ternary Complex with Compound 1, Atp-Gs and MG2P, PDB code: 3eqc:
Sodium binding site 1 out of 1 in 3eqc
Go back to
Sodium Binding Sites List in 3eqc
Sodium binding site 1 out
of 1 in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Ternary Complex with Compound 1, Atp-Gs and MG2P
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Sodium with other atoms in the Na binding
site number 1 of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Ternary Complex with Compound 1, Atp-Gs and MG2P within 5.0Å range:
|
Reference:
T.O.Fischmann,
C.K.Smith,
T.W.Mayhood,
J.E.Myers,
P.Reichert,
A.Mannarino,
D.Carr,
H.Zhu,
J.Wong,
R.S.Yang,
H.V.Le,
V.S.Madison.
Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors. Biochemistry V. 48 2661 2009.
ISSN: ISSN 0006-2960
PubMed: 19161339
DOI: 10.1021/BI801898E
Page generated: Mon Oct 7 08:54:27 2024
ISSN: ISSN 0006-2960
PubMed: 19161339
DOI: 10.1021/BI801898E
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