Sodium in PDB 2zsd: Pantothenate Kinase From Mycobacterium Tuberculosis (Mtpank) in Complex with Coenzyme A

All present enzymatic activity of Pantothenate Kinase From Mycobacterium Tuberculosis (Mtpank) in Complex with Coenzyme A:
2.7.1.33;

The structure of Pantothenate Kinase From Mycobacterium Tuberculosis (Mtpank) in Complex with Coenzyme A, PDB code: 2zsd was solved by B.Chetnani, S.Das, P.Kumar, A.Surolia, M.Vijayan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.99 / 2.50
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	103.840, 103.840, 89.604, 90.00, 90.00, 120.00
R / Rfree (%)	20.6 / 24

The binding sites of Sodium atom in the Pantothenate Kinase From Mycobacterium Tuberculosis (Mtpank) in Complex with Coenzyme A (pdb code 2zsd). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Pantothenate Kinase From Mycobacterium Tuberculosis (Mtpank) in Complex with Coenzyme A, PDB code: 2zsd:

Sodium binding site 1 out of 1 in the Pantothenate Kinase From Mycobacterium Tuberculosis (Mtpank) in Complex with Coenzyme A


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Pantothenate Kinase From Mycobacterium Tuberculosis (Mtpank) in Complex with Coenzyme A within 5.0Å range: probe atom residue distance (Å) B Occ A:Na900 b:58.3 occ:1.00 OD2 A:ASP124 2.8 51.9 1.0 N A:ARG193 3.1 54.5 1.0 OD1 A:ASP124 3.2 53.9 1.0 CG A:ASP124 3.4 50.0 1.0 CA A:VAL192 3.8 51.7 1.0 O A:VAL191 3.8 49.6 1.0 C A:VAL192 3.9 53.0 1.0 CA A:ARG193 4.0 54.1 1.0 CB A:ARG193 4.0 55.7 1.0 CD A:ARG122 4.0 58.4 1.0 CG A:ARG193 4.1 59.7 1.0 O A:ARG193 4.2 51.5 1.0 NE A:ARG122 4.2 61.5 1.0 O A:HOH358 4.2 60.9 1.0 C A:ARG193 4.4 52.5 1.0 CG A:ARG122 4.6 56.8 1.0 CG1 A:VAL192 4.6 50.8 1.0 C A:VAL191 4.6 49.2 1.0 N A:VAL192 4.7 50.6 1.0 CZ A:ARG122 4.7 61.8 1.0 CB A:VAL192 4.8 50.3 1.0 CB A:ASP124 4.8 46.9 1.0

B.Chetnani, S.Das, P.Kumar, A.Surolia, M.Vijayan. Mycobacterium Tuberculosis Pantothenate Kinase: Possible Changes in Location of Ligands During Enzyme Action Acta Crystallogr.,Sect.D V. 65 312 2009.
ISSN: ISSN 0907-4449
PubMed: 19307712
DOI: 10.1107/S0907444909002170