Sodium in the structure of Structural Dissection of Human Mitogen-Activated Kinase ERK1 (pdb 2zoq)

The binding sites of Sodium atom in the structure of Structural Dissection of Human Mitogen-Activated Kinase ERK1 (pdb code 2zoq). This binding sites where shown with 5.0 Angstroms radius around Sodium atom. The 2zoq structure was solved by T.KINOSHITA, T.TADA, S.NAKAE, I.YOSHIDA, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 45.6-2.4 Space group P1211 a (A) 62.382 b (A) 91.540 c (A) 64.930 alpha (°) 90.00 beta (°) 91.50 gamma (°) 90.00 Rfactor (%) n/a Rfree (%) n/a Sodium Binding Sites: Sodium binding site 1 out of 2 in 2zoq Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Sodium in the PDB 2zoq. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Sodium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Lys71, A: Gln122, A: Cys183, A: Asp184, A: 5id382, A: Hoh389, A: Hoh391, conact list: Atom Atom Distance (A) Na CE A:Lys71 3.88 Na NZ A:Lys71 3.80 Na OE1 A:Gln122 4.47 Na CB A:Cys183 4.34 Na SG A:Cys183 3.10 Na C A:Cys183 4.64 Na CA A:Cys183 4.69 Na N A:Asp184 3.57 Na CB A:Asp184 4.12 Na OD2 A:Asp184 3.74 Na OD1 A:Asp184 2.05 Na CG A:Asp184 3.09 Na CA A:Asp184 4.00 Na N9 A:5id382 4.94 Na IAE A:5id382 2.70 Na C8 A:5id382 3.62 Na C7 A:5id382 3.59 Na O5' A:5id382 4.33 Na O A:Hoh389 2.62 Na O A:Hoh391 4.86 interactive model: Sodium binding site 2 out of 2 in 2zoq Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Sodium in the PDB 2zoq. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Sodium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: Lys71, B: Gln122, B: Cys183, B: Asp184, B: 5id382, B: Hoh432, B: Hoh518, conact list: Atom Atom Distance (A) Na CE B:Lys71 4.01 Na CD B:Lys71 4.82 Na NZ B:Lys71 3.59 Na OE1 B:Gln122 4.89 Na CB B:Cys183 3.20 Na SG B:Cys183 3.09 Na C B:Cys183 4.00 Na CA B:Cys183 4.19 Na N B:Asp184 3.13 Na CB B:Asp184 3.98 Na OD2 B:Asp184 4.23 Na OD1 B:Asp184 2.11 Na CG B:Asp184 3.28 Na CA B:Asp184 3.69 Na N9 B:5id382 4.79 Na IAE B:5id382 2.92 Na C3' B:5id382 4.92 Na C8 B:5id382 3.57 Na C5 B:5id382 4.95 Na C7 B:5id382 3.61 Na C5' B:5id382 4.38 Na O5' B:5id382 4.75 Na O B:Hoh432 2.80 Na O B:Hoh518 4.66 interactive model: