Sodium in PDB 2zka: Urate Oxidase Complexed with 8-Azaxanthine Under 1.0 Mpa Oxygen Pressure

All present enzymatic activity of Urate Oxidase Complexed with 8-Azaxanthine Under 1.0 Mpa Oxygen Pressure:
1.7.3.3;

The structure of Urate Oxidase Complexed with 8-Azaxanthine Under 1.0 Mpa Oxygen Pressure, PDB code: 2zka was solved by N.Colloc'h, L.Gabison, M.Chiadmi, J.H.Abraini, T.Prange, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.97 / 1.61
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	80.172, 96.227, 105.408, 90.00, 90.00, 90.00
R / Rfree (%)	17.3 / 19

The binding sites of Sodium atom in the Urate Oxidase Complexed with 8-Azaxanthine Under 1.0 Mpa Oxygen Pressure (pdb code 2zka). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Urate Oxidase Complexed with 8-Azaxanthine Under 1.0 Mpa Oxygen Pressure, PDB code: 2zka:

Sodium binding site 1 out of 1 in the Urate Oxidase Complexed with 8-Azaxanthine Under 1.0 Mpa Oxygen Pressure


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Urate Oxidase Complexed with 8-Azaxanthine Under 1.0 Mpa Oxygen Pressure within 5.0Å range: probe atom residue distance (Å) B Occ A:Na303 b:20.9 occ:1.00 O A:ILE88 2.3 20.9 1.0 O A:HOH558 2.3 34.7 1.0 O A:ILE94 2.4 19.0 1.0 O A:TYR91 2.6 21.1 1.0 OE1 A:GLU136 2.7 32.8 1.0 O A:ASN92 3.2 25.6 1.0 C A:ILE88 3.3 20.2 1.0 C A:ILE94 3.5 18.0 1.0 CD A:GLU136 3.6 33.9 1.0 C A:TYR91 3.6 21.7 1.0 C A:ASN92 3.6 23.6 1.0 CA A:ILE88 3.8 19.6 1.0 OE2 A:GLU136 3.9 37.6 1.0 CA A:ASN92 3.9 24.6 1.0 ND1 A:HIS95 4.1 25.4 1.0 N A:ILE94 4.1 19.2 1.0 N A:ASN92 4.2 22.9 1.0 CB A:ILE88 4.2 20.1 1.0 CA A:ILE94 4.3 18.4 1.0 N A:HIS93 4.4 22.2 1.0 N A:HIS95 4.5 17.4 1.0 N A:GLU89 4.5 20.3 1.0 CE1 A:HIS95 4.6 27.0 1.0 CA A:HIS95 4.6 17.9 1.0 O A:PHE87 4.7 18.8 1.0 CB A:ILE94 4.8 18.5 1.0 CA A:TYR91 4.8 20.8 1.0 CG A:GLU136 4.8 30.2 1.0 N A:TYR91 4.8 20.5 1.0 C A:HIS93 4.9 20.2 1.0 CA A:GLU89 4.9 21.3 1.0

N.Colloc'h, L.Gabison, G.Monard, M.Altarsha, M.Chiadmi, G.Marassio, J.Sopkova-De Oliveira Santos, M.El Hajji, B.Castro, J.H.Abraini, T.Prange. Oxygen Pressurized X-Ray Crystallography: Probing the Dioxygen Binding Site in Cofactorless Urate Oxidase and Implications For Its Catalytic Mechanism. Biophys.J. V. 95 2415 2008.
ISSN: ISSN 0006-3495
PubMed: 18375516
DOI: 10.1529/BIOPHYSJ.107.122184