Sodium in PDB 2xzi: The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural and Mechanistic Insights

All present enzymatic activity of The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural and Mechanistic Insights:
3.2.1.18;

The structure of The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural and Mechanistic Insights, PDB code: 2xzi was solved by J.C.Telford, J.H.F.Yeung, M.J.Kiefel, A.G.Watts, S.Hader, J.Chan, A.J.Bennet, M.M.Moore, G.L.Taylor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.31 / 1.45
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	75.810, 57.990, 94.830, 90.00, 100.14, 90.00
R / Rfree (%)	17.917 / 20.459

The binding sites of Sodium atom in the The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural and Mechanistic Insights (pdb code 2xzi). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural and Mechanistic Insights, PDB code: 2xzi:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural and Mechanistic Insights


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural and Mechanistic Insights within 5.0Å range: probe atom residue distance (Å) B Occ A:Na502 b:12.3 occ:1.00 O A:HOH2237 2.3 12.8 1.0 O A:GLY116 2.3 13.3 1.0 OD1 A:ASN89 2.4 10.5 1.0 O A:GLY118 2.4 16.6 1.0 OD1 A:ASP87 2.4 12.6 1.0 O A:HOH2168 2.5 21.3 1.0 C A:GLY116 3.4 12.7 1.0 CG A:ASN89 3.4 9.6 1.0 CG A:ASP87 3.5 12.2 1.0 C A:GLY118 3.6 15.3 1.0 ND2 A:ASN89 3.7 13.2 1.0 OD2 A:ASP87 3.9 14.6 1.0 CA A:GLY116 4.0 11.7 1.0 O A:HOH2071 4.2 40.5 1.0 C A:SER117 4.2 14.8 1.0 O A:SER117 4.2 15.2 1.0 N A:GLY118 4.3 15.2 1.0 CA A:ALA119 4.4 14.0 1.0 N A:ALA119 4.4 14.4 1.0 N A:SER117 4.4 13.9 1.0 O A:GLY120 4.4 11.1 1.0 O A:ILE88 4.5 7.5 1.0 CA A:GLY118 4.6 15.7 1.0 CB A:ASN89 4.7 8.0 1.0 CA A:SER117 4.8 14.9 1.0 C A:ILE88 4.8 7.0 1.0 CB A:ASP87 4.8 10.1 1.0 N A:ILE88 4.8 7.4 1.0 C A:ALA119 5.0 13.2 1.0 N A:ASN89 5.0 6.8 1.0

Sodium binding site 2 out of 2 in the The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural and Mechanistic Insights


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural and Mechanistic Insights within 5.0Å range: probe atom residue distance (Å) B Occ B:Na502 b:13.1 occ:1.00 O B:HOH2148 2.2 28.0 1.0 O B:HOH2211 2.3 18.6 1.0 OD1 B:ASN89 2.3 13.6 1.0 O B:GLY118 2.4 18.9 1.0 OD1 B:ASP87 2.5 10.6 1.0 O B:GLY116 2.5 15.6 1.0 CG B:ASN89 3.3 9.8 1.0 C B:GLY116 3.5 13.9 1.0 CG B:ASP87 3.6 9.9 1.0 ND2 B:ASN89 3.6 13.1 1.0 C B:GLY118 3.6 17.9 1.0 OD2 B:ASP87 4.0 13.2 1.0 CA B:GLY116 4.1 12.1 1.0 O B:SER117 4.3 15.6 1.0 C B:SER117 4.4 16.4 1.0 CA B:ALA119 4.4 16.9 1.0 N B:ALA119 4.5 17.4 1.0 N B:GLY118 4.5 17.0 1.0 O B:ILE88 4.5 7.3 1.0 O B:GLY120 4.5 12.3 1.0 O B:HOH2146 4.5 21.7 1.0 N B:SER117 4.6 15.8 1.0 CA B:GLY118 4.6 17.5 1.0 CB B:ASN89 4.7 8.2 1.0 N B:ILE88 4.8 7.2 1.0 C B:ILE88 4.8 7.0 1.0 CB B:ASP87 4.8 8.0 1.0 C B:ALA119 4.9 16.3 1.0 CA B:SER117 4.9 16.4 1.0

J.C.Telford, J.H.F.Yeung, G.Xu, M.J.Kiefel, A.G.Watts, S.Hader, J.Chan, A.J.Bennet, M.M.Moore, G.L.Taylor. The Aspergillus Fumigatus Sialidase Is A Kdnase: Structural and Mechanistic Insights. J.Biol.Chem. V. 286 10783 2011.
ISSN: ISSN 0021-9258
PubMed: 21247893
DOI: 10.1074/JBC.M110.207043